2,3-Dihydrosciadopitysin - CAS 34421-19-7
Catalog number: 34421-19-7
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C33H26O10
Molecular Weight:
582.6
COA:
Inquire
Chemical Family:
Flavonoids
Description:
2,3-Dihydrosciadopitysin isolated from the hertwoods of Podocarpus macrophyllus.
Purity:
0.96
Appearance:
Yellow powder
Synonyms:
2,3-Dihydro-5,5'',7''-trihydroxy-4',4''',7-trimethoxy-3',8''-biflavone
MSDS:
Inquire
Quality Standard:
Enterprise Standard
Quantity:
Milligrams-Grams
1.2,3-Dihydrobiflavone from Ginkgo biloba.
Krauze-Baranowska M;Sowiński P Planta Med. 1999 Jun;65(5):482-4.
From the yellow leaves of Ginkgo biloba 2,3-dihydrosciadopitysin (5,5'',7''-trihydroxy-7,4',4'''-trimethoxy-3',8''-flavanone/flavone) was isolated as a mixture of two diastereomers. Its structure was elucidated employing 2D NMR techniques.
2.New constituent from Podocarpus macrophyllus var. macrophyllus shows anti-tyrosinase effect and regulates tyrosinase-related proteins and mRNA in human epidermal melanocytes.
Cheng KT;Hsu FL;Chen SH;Hsieh PK;Huang HS;Lee CK;Lee MH Chem Pharm Bull (Tokyo). 2007 May;55(5):757-61.
A new biflavonoid, 2,3-dihydro-4',4'''-di-O-methylamentoflavone (5), and five known compounds, (-)-catechin (1), quercetin (2), 2,3-dihydrosciadopitysin (3), sciadopitysin (4), and isoginkgetin (6), were isolated from Podocarpus macrophyllus var. macrophyllus (Podocarpaceae). These compounds were evaluated their ability to inhibit cellular tyrosinase activity and for their melanin inhibitory activity in human epidermal melanocytes (HEMn). In the melanin synthesis assay, 2,3-dihydro-4',4'''-di-O-methylamentoflavone (5) showed a potent anti-tyrosinase effect with IC(50)=0.098 mM in HEMn. It also significantly decreased both protein and mRNA levels of the tyrosinase-related protein-2 (TRP-2) by Western blot and quantitative real-time PCR (qRT-PCR) analysis. These findings suggest that the new compound, 2,3-dihydro-4',4'''-di-O-methylamentoflavone (5), is the most active component of P. macrophyllus var. macrophyllus in inhibiting pigmentation and that this inhibition is exerted through inhibition of transcription of the genes encoding TRP2.
3.Antifungal activity of biflavones from Taxus baccata and Ginkgo biloba.
Krauze-Baranowska M;Wiwart M Z Naturforsch C. 2003 Jan-Feb;58(1-2):65-9.
Bilobetin and 4'''-O-methylamentoflavone were isolated and identified in the needles of Taxus baccata, for the first time in this species. The antifungal activity of biflavones from T. baccata and Ginkgo biloba, namely amentoflavone, 7-O-methylamentoflavone, bilobetin, ginkgetin, sciadopitysin and 2,3-dihydrosciadopitysin towards the fungi Alternaria alternata, Fusarium culmorum, Cladosporium oxysporum was determined employing computer-aided image analysis couplet to a microscope. Bilobetin exhibited a significant antifungal activity with values of ED50 14, 11 and 17 microM respectively. This compound completely inhibited the growth of germinating tubes of Cladosporium oxysporum and Fusarium culmorum at a concentration 100 microM. Activity of ginkgetin and 7-O-methylamentoflavone towards Alternaria alternata was stronger than that of bilobetin. Moreover, slight structural changes in the cell wall of Alternaria alternata exposed to ginkgetin at concentration of 200 microM were observed.
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Flavonoids Products


CAS 41451-75-6 Bruceantin

Bruceantin
(CAS: 41451-75-6)

Bruceantin is a pharmacological agent which has been shown to induce apoptosis in human promyelocytic leukemia cells. Antiamoebic agent.

CAS 22688-78-4 Kaempferol-3-β-O-glucuronide

Kaempferol-3-β-O-glucuronide
(CAS: 22688-78-4)

Kaempferol-3-beta-O-glucuronide belongs flavonoid glucuronides, which can be found in vegetables and deconjugated by microsomal β-glucuronidase from various hum...

CAS 59870-68-7 Glabridin

Glabridin
(CAS: 59870-68-7)

Glabridin is a bio-available isoflavan isolated from licorice (Glycyrrhiza glabra L.) root extract. It has been reported to posses varies biological activities ...

CAS 15486-33-6 3,5-Dihydroxy-4',7-dimethoxyflavone

3,5-Dihydroxy-4',7-dimethoxyflavone
(CAS: 15486-33-6)

3,5-Dihydroxy-4',7-dimethoxyflavone is a natural flavonoid found in the herb of Andrographis paniculata (Burm. f.) Nees.

Angophorol
(CAS: 133442-54-3)

Angophorol isolated from the barks of Cephalotaxus sinensis.

CAS 211799-56-3 2',4',5'-Trimethoxy-2'',2''-dimethylpyrano[5'',6'':6,7]isoflavone

2',4',5'-Trimethoxy-2'',2''-dimethylpyra
(CAS: 211799-56-3)

2',4',5'-Trimethoxy-2'',2''- dimethylpyrano[5'',6'':6,7]isoflavone isolated from the herbs of Millettia ichthyochtona

CAS 13241-33-3 Neohesperidin

Neohesperidin
(CAS: 13241-33-3)

Neohesperidin is an intensive sweetener widely used in food and feed industry.

CAS 113963-41-0 Andrographidine E

Andrographidine E
(CAS: 113963-41-0)

Andrographidine E is extracted from the herbs of Andrographis paniculata.

CAS 1223097-20-8 6"-O-Acetylisovitexin

6"-O-Acetylisovitexin
(CAS: 1223097-20-8)

6"-O-Acetylisovitexin is a natural compound isolated from the herbs of Vitex negundo L.

CAS 852638-61-0 Heteronoside

Heteronoside
(CAS: 852638-61-0)

Heteronoside isolated from the herbs of Leonurus artemisia.

Neochamaejasmin B
(CAS: 90411-12-4)

Neochamaejasmin B isolated from the roots of Stellera chamaejasme Linn.

3,7,4'-Trihydroxy-5-methoxy-8-prenylflav
(CAS: 204935-85-3)

A compound of the flavonoid class found in the seeds of Cassia obtusifolia L.

CAS 482-39-3 Afzelin

Afzelin
(CAS: 482-39-3)

Afzelin isolated from the herbs of Thesium chinense Turcz. It effectively treats asthma is based on reduction of Th2 cytokine via inhibition of GATA‑binding pro...

CAS 1038753-13-7 4'-O-Methyllicoflavanone

4'-O-Methyllicoflavanone
(CAS: 1038753-13-7)

4'-O-Methyllicoflavanone is a flavonoid compound found in the herbs of Erythrina arborescens.

CAS 482-01-9 Homoferreirin

Homoferreirin
(CAS: 482-01-9)

Homoferreirin is a natural flavonoid found in the herbs of Desmodium sequax.

Dodonaflavonol
(CAS: 1392213-93-2)

Dodonaflavonol is a natural organic compound.

CAS 114482-86-9 Oroxin B

Oroxin B
(CAS: 114482-86-9)

Flavonoids

CAS 121747-89-5 Isoderrone

Isoderrone
(CAS: 121747-89-5)

Isoderrone is a natural flavonoid compound found in the herbs of Cudrania tricuspidata.

CAS 54542-51-7 6"-O-Acetylisoquercitrin

6"-O-Acetylisoquercitrin
(CAS: 54542-51-7)

6"-O-Acetylisoquercitrin is extracted from the leaves of Morus alba L. It is found in foods of plant origin. It is a NADPH oxidase inhibitor and shows antioxida...

Quick Inquiry

Verification code

Featured Items