|Description||2,3-DCPE hydrochloride is a compound that selectively induces apoptosis and downregulates Bcl-XL protein expression in multiple human cancer cells versus normal cells in vitro. It also specifically cleaves caspase-8, caspase-3, caspase-9, and poly(ADP-ribose) polymerase in cancer cells.|
|Purity||≥99% by HPLC|
Trametinib is a highly specific and potent MEK1/2 inhibitor with IC50 of 0.92 nM/1.8 nM and no inhibition of the kinase activities of c-Raf, B-Raf, ERK1/2.
SEA0400 is a selective inhibitior of Na+/Ca2+ exchanger. In an MPTP mouse model of Parkinson's disease, SEA0400 prevents dopaminergic neurotoxicity. It has an o...
Rolofylline metabolite M1-trans
Rolofylline metabolite M1-trans, an active metabolite of Rolofylline, is a potent and selective adenosine A1 receptor antagonist.
glucagon receptor antagonists-4
glucagon receptor antagonists-4 is a potent glucagon receptor antagonist with great oral bioavailability in vivo.
Thioguanine incorporation alters the DNA cleavage induced by topoisomerase II in the presence and absence of etoposide
6-O-α-D-Maltosyl-β-cyclodextrin is a cellular cholesterol modifier which can form soluble inclusion complex with cholesterol and is much less cytotoxic to human...
Chlorpheniramine inhibits the proliferation of MCF-7, MDA-MB 231, and Ehrlich cells in a dose-response manner, and significantly reduces the ornithine decarboxy...
UFP-101 is a potent, selective and competitive silent antagonist for the NOP opioid receptor, displaying > 3000-fold selectivity over δ, μ and κ opioid receptor...