|Molecular Formula||C20H24N10O12P2 (free acid)|
|Molecular Weight||658.4 (free acid)|
|Description||2',2''-Di-c-didGMP is an analogue of c-diGMP, the bacterial second messenger, which selectively binds the c-diGMP class II riboswitch. It can be used to discriminate between class I and class II of c-diGMP-binding RNAs and to study RNA-based c-diGMP signalling.|
|Purity||≥ 95% by HPLC|
|Synonyms||2'- , 2''- Dideoxy- cyclic diguanosine monophosphate, sodium salt|
Sp-6-Cl-cPuMPS is a PDE-resistant activator of protein kinase A that can be modified in position 6.
2'-AHC-c-diAMP is an analogue of c-diAMP, the bacterial second messenger, which can be used as a ligand for affinity chromatography or for coupling of labelling...
Sp-8-BnT-2'-O-Me-cAMPS is the most potent 2'-substituted activator of Epac2. In human osteosarcoma U2OS cell lines expressing Epac1 or Epac2, Sp-8-BnT-2'-O-Me-c...
8-AHA-2'-O-Me-cAMP is a ligand in affinity chromatography of cAMP binding proteins that do not require an intact 2'-OH group, such as the exchange protein activ...
2'-NH2-cAMP is often used in affinity chromatography of cAMP and cGMP binding proteins for its amino group used as a ligand, which do not require an intact 2'-O...
Sp-2-Cl-cAMPS is an analogue of Sp-cAMPS, the protein kinase A stimulator. The chlorine atom in position 2 of adenine nucleobase significantly increase the stab...
8-Br-cGMP is a stimulator of cGMP dependent protein kinases I α, I β & type II and cGMP-gated ion channels (cGMP agonist). Compared to cGMP, it has a superior s...
Rp-2'-AHC-cGMPS-Agarose is the PDE-resistant PKG inhibitor Rp-cGMPS immobilized on agarose by an aminohexylcarbamoyl spacer, which can be used in affinity chrom...
c-(Ap-8-Br-Gp) is an analogue of c-(ApGp), the potential bacterial second messenger, which is used for binding studies and as precursor for further modification...
cAMP-AM is a membrane-permeant precursor of cAMP, the second messenger. cAMP is released after permeation and metabolism of cAMP-AM by esterases, then it is met...
Sp-8-Br-cGMPS is an activator of protein kinase G I α and protein kinase A. It has a resistant effect against cyclic nucleotide phosphodiesterases. Compared to ...
2'-AHC-cAMP-Agarose is the protein kinase A activator cAMP immobilized on agarose by an aminohexylcarbamoyl spacer, which can be used in affinity chromatography...
Sp-cAMPS, sodium salt
Sp-cAMPS is an activator of protein kinase A (cAMP agonist). It exhibits high resistance against cyclic nucleotide phosphodiesterases and membrane permeability ...
8-CPT-cAMP-AM is a precursor of 8-CPT-cAMP, the PKA activator. 8-CPT-cAMP is released after the metabolism of 8-CPT-cAMP-AM by esterases.
2',2''-Di-Biotin-16-c-diAMP is an analogue of c-diAMP, the bacterial second messenger. It is a potential tracer in immunoassays and commonly used for affinity c...
2'-AEC-cGMP-Agarose is the protein kinase G activator cGMP immobilized on agarose by an aminoethylcarbamoyl spacer, which can be used in affinity chromatography...
6-AE-8-N3-cAMP is a photosensitive analogue for photoaffinity labelling. It can be immobilized by the irradiation of UV light. The amino group in position 6 of ...