|Description||(1S,3R)-ACPD, an isomer of (±)-trans-ACPD, has been found to be an agonist of mGluRs.|
|Purity||≥98% by HPLC|
(±)-ADX 71743 has been found to be a negative allosteric modulator at mGlu7 and is brain penetrant.
AZ 12216052 is a positive allosteric modulator of mGluR8. It reduced measures of anxiety in wild-type male mice and is used as a therapeutic target for anxiety ...
(1S,3R)-ACPD, an isomer of (±)-trans-ACPD, has been found to be an agonist of mGluRs.
L-AP4 is a selective group III metabotropic glutamate receptor (mGluR) agonist. It also acts as an agonist at the quisqualate-sensitized AP6 site in hippocampus...
XAP 044 is a potent, selective and brain penetrating mGlu7 antagonist (IC50 = 88 nM). It inhibits lateral amygdala long term potentiation (LTP) in brain slices ...
Desmethyl-YM 298198 is a derivative of YM 298198, a selective antagonist of mGlu1.
DL-AP3 has been found to be an inhibitor of mGluR as well as HPSP.
(1R,2S)-VU0155041 is a partial mGluR4-positive allosteric modulator (EC50= 2.35 μM) that dependently attenuated hyperalgesia in neuropathic pain model rats.