|Description||[18F]Fluciclovine is a 18F-labeled analog of the amino acid L-leucine. It is used as a diagnostic agent for PET imaging to detect prostate cancer relapse.|
|Brife Description||diagnostic agent, detection of prostate cancer relapse|
|Synonyms||Axumin; anti-1-amino-3-18F-fluorocyclobutane-1-carboxylic acid|
|Application||detection of prostate cancer relapse|
|Current Developer||Blue Earth Diagnostics|
Parasin I, a 19-amino acid histone H2A-derived peptide isolated from the skin of the catfish, is a cell permeable cationic antimicrobial agent.
TPC-144 is a novel and selective LSD1 inhibitor potentially used for the treatment of acute myeloid leukemia (AML) and small cell lung cancer (SCLC). TPC-144 re...
Competitive AMPA/kainate antagonist. In rat cortical membranes, displays high affinity for [3H]-AMPA (Ki = 120 nM) and [3H]-CNQX (Ki = 32 nM) binding sites and ...
Edonentan, also known as BMS-207940, is a very potent and selective ETA endothelin receptor antagonist (Ki= 10 pM) that shows 80000-fold selective for ETA vs ET...
PF-562271 besylate is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivi...
Atazanavir is a HIV protease inhibitor with Ki of 2.66 nM. It is an antiretroviral drug of the protease inhibitor (PI) class. Like other antiretrovirals, it is ...
Clenproperol is a β-adrenergic agonist.
Sitaxentan sodium inhibits ET-1-induced stimulation of phosphoinositide turnover with a Ki of 0.69 nM and a pA2 of 8.0.