|Description||Alvespimycin, a synthetic Geldanamycin derivative, has been found to be a potent, H2O-soluble Hsp90 inhibitor. IC50: 62 nM.|
|Solubility||DMSO, Methanol, Ethanol|
|Storage||Store in a freezer upon arrival, at -10°C to -25°CUse the original container to store the product.Keep the lid tightly closed.Avoid exposing to strong direct light.Other vendors may recommend higher temperatures for storage.|
|Application||HSP-90 inhibitor; potential anti-cancer drug|
|Melting Point||148 °C-155 °C|
A cephamycin beta-lactam antibiotic grouped with the second generation cephalosporins
An early semi-synthetic erythromycin, prepared by reaction of the 9-keto moiety to methyl oxime; shows broad spectrum antibacterial and antiprotozoan activity a...
Avermectin B1a aglycone
An acid degradation product produced by hydrolysis of the disaccharide unit of avermectin; an inhibitor of nematode larval development; devoid of paralytic acti...
7-Amino-Actinomycin-D,a semisynthetic derivate of actinomycin, has been found to be able to bind to single stranded DNA and could be used as a fluorescent dye i...
Erythromycin A oxime
A semi-synthetic analogue of erythromycin; pivotal in the development of the ring expanded aza-erythromycins (e.g. Azithromycin) and the oxime ethers (e.g. Roxi...
A semi-synthetic analogue of avermectin B1b prepared by oxidation of the 4”-hydroxy moiety and reductive amination followed by acetylation; the minor component ...
A freely soluble aminoglycoside antibiotic similar in structure to streptomycin
Chloramphenicol succinate sodium
The salt prepared from chloramphenicol succinate using the free carboxylic acid of the succinate which ionises and readily forms in weakly sodium hydroxide solu...
A cephamycin antibiotic grouped with the second generation cephalosporins
A semi-synthetic, ring-expanded erythromycin, produced by a beckmann rearrangement of erythromycin oxime and reduction to the imine ether, followed by reductive...
A semi-synthetic antibiotic derived from desmycosin (tylosin B), a minor co-metabolite of tylosin; prepared by the partial hydrolysis of tylosin with the loss o...
Erythromycin A enol ether
A degradation product of erythromycin formed under acidic conditions by C6–OH internal attack on the C9 ketone to produce a cyclic enol ether; an important stan...
An extended spectrum beta-lactam antibiotic; similar in structure to ampicillin; can be combined with clavulanate potassium for greater efficacy against beta-la...
A degradation product of oxytetracycline formed under acidic conditions; an initial dehydration to anhydrooxytetracycline then undergoes an internal cyclisation...
The hydrochloride salt of a rare semi-synthetic tetracycline; prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of declomycin; acts by reve...
A sparingly soluble (1.4 mg/ml) bacterial protein synthesis inhibiting antibiotic
A semi-synthetic chloramphenicol analogue in which the dichloroacetamide is replaced with dibromoacetamide; possesses weak antibiotic activity
Erythromycin A N-oxide
A minor analogue of the erythromycin complex isolated from saccharopolyspora erythraea; a facile metabolite formed in vivo which can revert to erythromycin A un...
The salt of the semi-synthetic cyclic lipopeptide, micafungin; inhibits the synthesis of β-(1,3)-D-glucan, an essential component of the cell wall of susceptibl...
A semi-synthetic derivative of puromycin which lacks the methoxyphenylalanyl moiety; the key intermediate in the synthesis of semi-synthetic analogues of puromy...