|Targets||Nitric oxide synthase (NOS)|
|Description||1400W is a selective inducible nitric oxide synthase (NOS) inhibitor(Ki=7nM).By suppressing the induction of inducible NOS, 1400W exhibits an therapeutical effect on ischemia reperfusion injury,acute hypobaric hypoxia/reoxygenation-induced cognitive deficits and tumor.|
|Brife Description||iNOS inhibitor,Nitric oxide synthase (NOS),ischemia reperfusion injury,acute hypobaric hypoxia,tumor|
|Related CAS||180001-34-7 (Free base)|
|Synonyms||N-[[3-(aminomethyl)phenyl]methyl]-ethanimidamide, dihydrochloride; 1400W HCl; 1400W hydrochloride; 1400W (hydrochloride)|
|Solubility||Soluble to 100 mM in water|
|Storage||Store in a cool and dry place and at0-4℃ for short term(days to weeks)or -66℃ for long term(months to years).|
|Application||A selective inducible nitric oxide synthase (iNOS) inhibitor which has the potential for treatment of ischemia reperfusion injury,acute hypobaric hypoxia and tumor.|
|Shelf Life||2 years|
|Boiling Point||329ºC at 760 mmHg|
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1400W is a selective inducible nitric oxide synthase (NOS) inhibitor(Ki=7nM,IC50=2.0uM).By suppressing the induction of inducible NOS, 1400W exhibits an therape...
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