|Targets||Nitric oxide synthase (NOS)|
|Description||1400W is a selective inducible nitric oxide synthase (NOS) inhibitor(Ki=7nM,IC50=2.0uM).By suppressing the induction of inducible NOS, 1400W exhibits an therapeutical effect on ischemia reperfusion injury,acute hypobaric hypoxia/reoxygenation-induced cognitive deficits and tumor.|
|Brife Description||iNOS inhibitor,Nitric oxide synthase (NOS),ischemia reperfusion injury,acute hypobaric hypoxia,tumor|
|Synonyms||N-[[3-(AMINOMETHYL)PHENYL]METHYL]-ETHANIMIDAMIDE DIHYDROCHLORIDE; N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE; N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE 2HCL; N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE, DIHYDROCHLORIDE|
|Storage||Store in a cool and dry place and at0-4℃ for short term(days to weeks)or -66℃ for long term(months to years).|
|Application||A selective inducible nitric oxide synthase (iNOS) inhibitor. A long-acting human iNOS inhibitor possessing an IC50 value of 2.0uM.|
|Shelf Life||2 years|
1400W is a selective inducible nitric oxide synthase (NOS) inhibitor(Ki=7nM).By suppressing the induction of inducible NOS, 1400W exhibits an therapeutical effe...
FK-330 is a novel inducible nitric oxide synthase inhibitor for preventing ischemia and reperfusion injury in rat liver transplantation.
An endogenous inhibitor of nitric oxide (NO) synthase activity
Kuwanon A, a flavone derivative isolated from the root barks of the mulberry tree (Morus alba L.), inhibits nitric oxide production (IC50= 10.5 μM).
Aminoguanidine hydrochloride is the hydrochloride salt form of Aminoguanidine. Aminoguanidine is an inhibitor that has an irreversible function on iNOS with sel...
2,3 Diaminonaphthalene is a highly selective colorimetric and fluorometric reagent for selenium detection and also an inhibitor of nitric oxide (NO) formation.
Cindunistat hydrochloride maleate
Cindunistat is a selective Nitric oxide synthase (iNOS) type II inhibitor. It is potentially useful in patients with symptomatic osteoarthritis of the knee. But...
Ronopterin is a potent Nitric oxide synthase inhibitor used as a neuroprotectant.
Agmatine sulfate, the sulfate preparation of Agmatine, is an endogenous agonist at imidazoline receptor and a NO synthase inhibitor. Agmatine displaces clonidin...
GW 274150 is a potent, long-acting and highly selective inhibitor of iNOS which have a very high degree of selectivity for iNOS versus both eNOS (>100-fold) and...
Haloperidol hydrochloride is a dopamine antagonist that specifically targets D2-like receptors, with effect to treat schizophrenia, acute psychosis, and deliriu...
The dihydrobromide salt form of 1,4-PB-ITU, a carbamimidoylsulfanyl derivative, has been found to be an iNOS and nNOS inhibitor that has poor membrane permeabil...
1400W is a selective inducible nitric oxide synthase (NOS) inhibitor(Ki=7nM,IC50=2.0uM).By suppressing the induction of inducible NOS, 1400W exhibits an therape...
1,5-Isoquinolinediol is a PARP1 inhibitor (IC50 value 0.39 - 1.00 μM) and neuroprotective agent leading to an increase up to 8-fold in the absolute frequency of...