11β-HSD1-IN-1 - CAS 1203956-47-1
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C18H14ClF4N3O
Molecular Weight:
399.77
COA:
Inquire
Targets:
Others
Description:
11β-HSD1-IN-1 is an inhibitor of 11β-hydroxydehydrogenase 1 (11β-HSD1) (IC50= 52 nM).
Publictions citing BOC Sciences Products
  • >> More
Synonyms:
4H-1,2,4-Triazole, 3-(2-chloro-4-fluorophenyl)-4-methyl-5-[1-methyl-1-(2,4,6-trifluorophenoxy)ethyl]-
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
Boiling Point:
507.3±60.0 ℃ at 760 Torr
Density:
1.39±0.1 g/cm3
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Products


CAS 109581-93-3 Tacrolimus monohydrate

Tacrolimus monohydrate
(CAS: 109581-93-3)

Tacrolimus monohydrate is a potent immunosuppressive drug often administered to transplant recipient patients and exhibits a variety of adverse cardiovascular e...

CAS 383150-41-2 JTE-013

JTE-013
(CAS: 383150-41-2)

JTE-013 is a Potent and selective sphingosine-1-phosphate (S1P) receptor 2 (S1P2) antagonist (IC50=17.6 nM).

CAS 538-71-6 Domiphen Bromide

Domiphen Bromide
(CAS: 538-71-6)

Domiphen bromide is a quaternary ammonium antiseptic with actions as a cationic surfactant.

CAS 481-72-1 Aloe-emodin

Aloe-emodin
(CAS: 481-72-1)

Aloe-emodin is an interferon-inducing agent with IC50 of about 1 μg/mL for JEV and of about 0.33 μg/mL for EV71.

CAS 132-65-0 Dibenzothiophene

Dibenzothiophene
(CAS: 132-65-0)

Dibenzothiophene (DBT) is a model compound for organic sulfur in fossil fuels.

MK 410
(CAS: 40738-05-4)

MK 410 is an anti-inflammatory drug which can induce alterations in the immune system by the suppression of plasma neutral proteinase activity.

GSK256471
(CAS: 1133706-08-7)

This active molecular is a selective and potent NK(3) antagonist. It has a high affinity for recombinant human (pK(i) value 8.9) and native guinea pig (pK(i) va...

CAS 27975-19-5 Isosteviol

Isosteviol
(CAS: 27975-19-5)

A tetracyclic diterpenoid with a beyerane core has drawn attention because it can exhibit antihypertensive activity, reduce blood glucose, suppress cancer cells...

FR-218944
(CAS: 233264-02-3)

FR-218944 is a vasopressin antagonist compound.

UK 35493
(CAS: 113213-52-8)

This molecular is a biochemical.

CAS 176957-55-4 CCT007093

CCT007093
(CAS: 176957-55-4)

CCT007093 is a potent PPM1D inhibitor or WIP1 inhibitor that selectively reduces viability of human tumour cell lines

CAS 38647-11-9 Triptonide

Triptonide
(CAS: 38647-11-9)

Triptonide, extracted from Tripterygium wilfordii Hook, inhibited the proliferation of mouse splenocytes induced by suboptimal concentration of concanavalin A o...

CAS 794466-70-9 Vemakalant

Vemakalant
(CAS: 794466-70-9)

Vernakalant is an drug under regulatory for the treatment for conversion of atrial fibrillation. It blocks atrial potassium channels, thereby prolonging repolar...

CAS 856676-23-8 Choline Fenofibrate

Choline Fenofibrate
(CAS: 856676-23-8)

Choline Fenofibrate is the choline salt of fenofibric acid under clinical development as a combination therapy with rosuvastatin for the management of dyslipide...

ML281
(CAS: 1404437-62-2)

ML281, a quinoxalin derivative, has been found to be a STK33 inhibitor and could have probable effect against KRAS-dependent cancers. IC50: 14 nM.

CI 972
(CAS: 115787-68-3)

This active molecular is a potent purine nucleoside phosphorylase inhibitor and a T cell-selective immunosuppressive agent. CI-972 inhibited proliferation of hu...

CAS 1462249-75-7 PFK-158

PFK-158
(CAS: 1462249-75-7)

PFK-158, also known as ACT-PFK-158, is an inhibitor of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases (PFK-2/FBPase) isoform 3 (PFKFB3) and derivative of...

CAS 1665-48-1 Metaxalone

Metaxalone
(CAS: 1665-48-1)

Metaxalone is a muscle relaxant. The mechanism of action of metaxalone in humans is not fully understood. It was suggested that it acts through general central ...

CAS 312756-74-4 RS-1

RS-1
(CAS: 312756-74-4)

RS-1, a cell-permeable sulfonamido-benzamide compound that increases the DNA binding activity of RAD51 (Kd range = 48-107 nM, value depends on cofactors present...

CAS 543-15-7 Heptaminol Hydrochloride

Heptaminol Hydrochloride
(CAS: 543-15-7)

Heptaminol Hydrochloride is an amino alcohol which is classified as a vasoconstrictor used in the treatment of low blood pressure, particularly orthostatic hypo...

Chemical Structure

CAS 1203956-47-1 11β-HSD1-IN-1

Quick Inquiry

Verification code

Featured Items