|Description||11β-HSD1-IN-1 is an inhibitor of 11β-hydroxydehydrogenase 1 (11β-HSD1) (IC50= 52 nM).|
|Storage||Store in a cool and dry place (or refer to the Certificate of Analysis).|
|Boiling Point||507.3±60.0 ℃ at 760 Torr|
Dehydrocostus lactone and CL from root of S. lappa have anti-colorectal cancer activities through inhibiting Wnt/β-catenin pathway.
Nicodicosapent is a bio-active molecular as an antihypertrigylceridemic drug candidate.
Bucetin, a phenacetin analog, has antipyretic and analgesic effect. It has been discontinued for showing renal toxicity.
GW4869 is a cell-permeable, specific and non-competitive inhibitor of neutral sphingomyelinases (IC50 = 1 μM).
Disodium tartrate dihydrate
Disodium tartrate dihydrate is a Acid phosphatase inhibitor used in buffers for molecular biology and cell culture applications.
(R)-GNE-140 is a potent lactate dehydrogenase A (LDHA) inhibitor (IC50s= 3 nM for LDHA and 5 nM for LDHB), with 18-fold more potent than S enantiomer.
Erlosiban, an iminopyrrolidin derivative, has been found to be a nonpeptide oxytocin receptor antagonist that could probably be used in the treatment of female ...
ML-390 is an inhibitor of human DHODH, which induces differentiation in acute myeloid leukemia cell lines U937 (murine) and THP-1 (human) cell lines with an EC5...
Aminophenazone (or aminopyrine) is a pyrazolone with analgesic, anti-inflammatory, and antipyretic properties but has risk of agranulocytosis.
Ginsenoside Ro, the predominant ginsenoside in the rhizome, shows no hemolytic nor cytotoxic activities.
CDK2, a member of the eukaryotic S/T protein kinase family, catalyzes the phosphoryl transfer of ATP γ-phosphate to serine or threonine hydroxyl (denoted as S0/...
LTX-315, an oncolytic peptide with potent anticancer activity, kills cancer cells through Bax/Bak-regulated mitochondrial membrane permeabilization. LTX-315 inh...
kb-NB77-78 is an analog of CID797718, which is a by-product of the synthesis of the parental compound, CID755673(PKD1 inhibitor).
Kartogenin induces the selective differentiation of multipotent mesenchymal stem cells (MSCs) into chondrocytes. Kartogenin binds to filamin A, and disrupts the...
CI 924 is hypolipidemic agent. It can elevate anti-atherogenic HDL and lower VLDL.
Auranofin appears to induce heme oxygenase 1 (HO-1) mRNA, as an inhibitor of thioredoxin reductase (TrxR) (IC50 = 20 nM; Ki = 4 nM for the NADPH-reduced form of...
Piperidolate is a tertiary amine antimuscarinic. It is similar to atropine. It is mainly used in the smooth muscle spasm of the gastrointestinal tract and inhib...
CP-640186 is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respec...
Butylparaben is used as an antimicrobial preservative in cosmetics. It is also used in medication suspensions and used as a flavoring additive in food.
Bucladesine calcium salt
Bucladesine calcium salt is a membrane permeable selective activator of PKA. It is absorbed very rapidly and almost completely when the aqueous solution is appl...