|Targets||Nitric oxide synthase (NOS)|
|Description||The dihydrobromide salt form of 1,4-PB-ITU, a carbamimidoylsulfanyl derivative, has been found to be an iNOS and nNOS inhibitor that has poor membrane permeability in whole cells.|
|Synonyms||1,4-PB-ITU dihydrobromide; 1,4-PBIT dihydrobromide; EU-0100983; SCHEMBL2283156|
|Storage||Store in a cool and dry place and at 0 - 4 °C for short term (days to weeks) or -20 °C for long term (months to years).|
|Quality Standard||In-house standard|
L-NIO dihydrochloride is a nitric oxide synthase inhibitor. It can inhibit iNOS, eNOS and nNOS. Active in vivo.
2,4-Diamino-6-hydroxypyrimidine has been found to be a GCH1 inhibitor and could suppress the activity of NO synthase through preventing the synthesis of BH4.
GW 274150 is a potent, long-acting and highly selective inhibitor of iNOS which have a very high degree of selectivity for iNOS versus both eNOS (>100-fold) and...
ARL 17477 dihydrochloride
The hydrochloride salt form of ARL 17477, which has been found to be a nitric oxide synthase (NOS) inhibitor and could induce apoptosis/cell death in leukemia c...
The sulfate salt form of L-Canavanine, a homoserine analog, has been found to be a NO synthase inhibitor.
2,3 Diaminonaphthalene is a highly selective colorimetric and fluorometric reagent for selenium detection and also an inhibitor of nitric oxide (NO) formation.
TRIM is a potent inhibitor of neuronal and inducible NO synthases (nNOS and iNOS), but exhibits lower affinity for the endothelial isoform (IC50 = 28.2, 27.0 an...
(S)-Methylisothiourea sulfate is a more potent than NMMA as an inhibitor of inducible nitric oxide synthetase (iNOS). The Ki values are 120, 200, and 160 nM usi...