1,1,4,4-Tetramethyl-1,4-disila-5-oxacyclopentane - CAS 7418-20-4
Catalog number: 7418-20-4
Category: Main Product
Molecular Formula:
C6H16OSi2
Molecular Weight:
160.36200
COA:
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Purity:
95%
MSDS:
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Quantity:
Data not available, please inquire.
Boiling Point:
124ºC
Density:
0.855
1.Synthesis and antioxidant properties of novel benzimidazoles containing substituted indole or 1,1,4,4-tetramethyl-1,2,3,4-tetrahydro-naphthalene fragments.
Ateş-Alagöz Z1, Kuş C, Coban T. J Enzyme Inhib Med Chem. 2005 Aug;20(4):325-31.
Some 6-fluoro-5-substituted-benzimidazole derivatives in which indole and 1,1,4,4-tetramethyl-1,2,3,4-tetrahydro-naphthalene groups were attached to the 2-position of the benzimidazole ring were synthesized and tested for antioxidant properties in vitro. Almost all the synthesized compounds at the 10(-3) M concentrations showed superoxide anion scavenging activity. Compounds 5, 3, 9, 4, 17 and 13 have strong inhibitory effects on superoxide anion formation (98%, 93%, 91%, 88%, 85% and 81%, respectively) at 10(-3) M concentration and these results are better than 30 IU of superoxide dismutase (SOD) (76%). Compound 11 is the most effective scavenger of 2,2-diphenyl-1-picrylhydrazyl (DPPH) stable free radical at 10(-3)M (61%) concentration.
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Chemical Structure

CAS 7418-20-4 1,1,4,4-Tetramethyl-1,4-disila-5-oxacyclopentane

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