(+)-UH 232 MALEATE - CAS 95999-12-5
Category:
Main Product
Product Name:
(+)-UH 232 MALEATE
Catalog Number:
95999-12-5
Synonyms:
(+)-UH 232 MALEATE; CIS-(+)-5-METHOXY-1-METHYL-2-(DI-N-PROPYLAMINO)TETRALIN MALEATE; [1S,2R,(+)]-1,2,3,4-Tetrahydro-5-methoxy-1α-methyl-N,N-dipropyl-2α-naphthalenamine
CAS Number:
95999-12-5
Molecular Weight:
391.5
Molecular Formula:
C22H33NO5
COA:
Inquire
MSDS:
Inquire
Chemical Structure
CAS 95999-12-5 (+)-UH 232 MALEATE

Reference Reading


1.Synergistic interactions between the NMDA antagonist dizocilpine and the preferential dopamine autoreceptor antagonists (+)-AJ 76 and (+)-UH 232 with regard to locomotor stimulation in monoamine-depleted mice.
Svensson A1, Carlsson M, Carlsson A. J Neural Transm Gen Sect. 1991;85(1):69-77.
When administered to mice pretreated with the monoamine-depleter reserpine and the catecholamine synthesis inhibitor alpha-methyl-para-tyrosine, the preferential autoreceptor antagonists (+)-AJ76 and (+)-UH 232 induced weak locomotor stimulation. When either (+)-AJ 76 or (+)-UH 232 was combined with a subthreshold dose of the selective NMDA antagonist dizocilpine (MK-801), a marked locomotor stimulation was produced in monoamine-depleted mice. The mechanism of this stimulation, although reduced by dopamine antagonists, remains to be clarified.