Tubulysin B - CAS 205304-87-6
Not Intended for Therapeutic Use. For research use only.
Category:
ADCs
Product Name:
Tubulysin B
Synonyms:
(2S,4R)-2-Methyl-4-[2-[(1R,3R)-1-acetoxy-3-[[N-[[(2R)-1-methyl-2beta-piperidinyl]carbonyl]-L-isoleucyl](butanoyloxymethyl)amino]-4-methylpentyl]thiazole-4-ylcarbonylamino]-5-(4-hydroxyphenyl)pentanoic acid;
CAS Number:
205304-87-6
Description:
Tubulysin B is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Molecular Weight:
830.06
Molecular Formula:
C42H63N5O10S
COA:
Inquire
MSDS:
Inquire
Canonical SMILES:
CCCC(=O)OCN(C(CC(C1=NC(=CS1)C(=O)NC(CC2=CC=C(C=C2)O)CC(C)C(=O)O)OC(=O)C)C(C)C)C(=O)C(C(C)CC)NC(=O)C3CCCCN3C
InChI:
InChI=1S/C42H63N5O10S/c1-9-13-36(50)56-24-47(41(53)37(26(5)10-2)45-39(52)33-14-11-12-19-46(33)8)34(25(3)4)22-35(57-28(7)48)40-44-32(23-58-40)38(51)43-30(20-27(6)42(54)55)21-29-15-17-31(49)18-16-29/h15-18,23,25-27,30,33-35,37,49H,9-14,19-22,24H2,1-8H3,(H,43,51)(H,45,52)(H,54,55)/t26-,27-,30+,33+,34+,35+,37-/m0/s1
InChIKey:
HWCIETDQUHYHGQ-YHVCZDCZSA-N
Tag:
ADCs Cytotoxin

Related ADCs Cytotoxin Products


CAS 112300-33-1 Ethoquine

Ethoquine
(CAS: 112300-33-1)

AChR agonist. Rigid bicyclic analog of ACh and ARECOLINE. Good penetration of biological membranes. Quinuclidine derivative, , synthetic.

CAS 126-17-0 Solasodine

Solasodine
(CAS: 126-17-0)

Solasodine(Purapuridine) is a poisonous alkaloid chemical compound that occurs in plants of the Solanaceae family. Solasodine showed selective cytotoxicity agai...

Cardiotoxin
(CAS: 56574-47-1)

A cytolytic toxin that causes depolarization of skeletal muscle fibers in vitro. Stimulates Ca2+ transport and ATP hydrolysis by the sarcolemmal Ca2+/Mg2+-ATPas...

DM4
(CAS: 796073-69-3)

DM 4 is an intermediate used to prepare semisynthetic maytansine analogs which can be conjugated with antibodies for the targeted treatment of cancer.

CAS 537-30-4 Convolvine

Convolvine
(CAS: 537-30-4)

an anesthetic acting on the nerve endings, with a good selectivity on sensory nerves; lowers arterial pressure; vasodilator. Tropane alkaloid , from plants of t...

CAS 6681-13-6 Hernandezine

Hernandezine
(CAS: 6681-13-6)

Anti-tumor effect of hernandezine and other components extracted from Thalictrum glandulosissimum.

CAS 10605-21-7 Melamine

Melamine
(CAS: 10605-21-7)

Melamine is a widely used, broad-spectrum benzimidazole fungicide and a metabolite of benomyl. It is also employed as a casting worm control agent in amenity tu...

CAS 95751-30-7 Charybdotoxin

Charybdotoxin
(CAS: 95751-30-7)

Ca2+-Activated K+ Channel Blocker

Sevedindione

Sevedindione presents an antiarrhythmic activity on arrhythmias caused by Aconitine.

Alpha-Cobratoxin
(CAS: 769933-79-1)

α-Cobratoxin is a substance of the venom of certain Naja cobras. It is a nicotinic acetylcholine receptor (nAChR) antagonist which causes paralysis by preventin...

CAS 87777-29-5 Morphiceptin

Morphiceptin
(CAS: 87777-29-5)

Morphiceptin is a four amino acid peptide derived from the ß-casomorphin, a protein fragment itself derived from the digestion of milk protein casein. It is one...

ShK – Stichodactyla toxin
(CAS: 165168-50-3)

ShK (Stichodactyla helianthus Neurotoxin) has been isolated from the venom of the Carribean sea anemone Stoichactis helianthus. ShK inhibits voltage-dependent p...

CAS 220355-66-8 Saxitoxin diacetate

Saxitoxin diacetate
(CAS: 220355-66-8)

Saxitoxin (STX) is a potent neurotoxin and the best-known paralytic shellfish toxin (PST). Ingestion of saxitoxin, usually by consumption of shellfish contamina...

CAS 130288-24-3 Duocarmycin SA

Duocarmycin SA
(CAS: 130288-24-3)

Duocarmycin SA is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.

Bj-xtrlT (recombinant)

An excitatory scorpion toxin. Polypeptide, of 77 amino acids cross-linked by 4 disulfide bridges. Recombinant toxin produced in<br/>Escherichia coli initialy fr...

Benzoylheteratisine hydrochloride
(CAS: 1262758-10-0)

A Na+ channel blocker; potent antiarrhythmic, inhibits voltage-gated Na+ channels in rat brain synaptosomes.

CAS 90-47-1 Xanthone

Xanthone
(CAS: 90-47-1)

Xanthonoid Purified from Hypericum perforatum

CAS 17946-87-1 Leucomisine

Leucomisine
(CAS: 17946-87-1)

Sesquiterpene lactone , from plants of the Compositae family, an antiatherosclerotic, angioprotective, hypolipidemic and anti-inflammatory.

CAS 3563-63-1 Diquine

Diquine
(CAS: 3563-63-1)

a nicotinic cholinoreceptor antagonist at the neuromuscular junction; curare-like ganglioblocker. Bis-quaternary quinuclidine derivative, , synthetic.

Q Pr

Synthetic, nicotinic AChR. Rigid bicyclic analog of TMA and TEA.