Mebicyphat is shown to be a non-competitive GABA antagonist. Blocks GABA gated Cl- channels, and is shown to inhibit dihydropicrotoxin
Anti-inflammatory, antioxidant and free radical scavenger. Inhibits LPS-induced TNF-α, IL-6 and inducible nitric oxide production and blocks NF-κB and AP-1 acti...
Synthetic, nicotinic AChR. Rigid bicyclic analog of TMA and TEA.
Long-acting, centrally active acetylcholinesterase inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors. Prevents β-amyloid-...
Protopine is a benzylisoquinoline alkaloid occurring in opium poppy, Corydalis tubers and other plants of the family papaveraceae, like Fumaria officinalis. It ...
A neuronal nicotinic AChR antagonist, blocking superior cervical sympathetic ganglion
Terpenoids found in the umbelliferae family act as agonists/antagonists for ER(alpha) and Erbeta.
Ruthenium red is a polycationic dye that inhibits sarcoplasmic reticulum Ca2+ release, blocks Ca2+ uptake and release from mitochondria, and prevents Ca2+ relea...
A nicotinic antagonist.
Seco-Duocarmycin TM is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Potent antagonist for α7-containing neuronal nicotinic receptors (Ki = 1.4 nM). Interacts with α4β2 and α6β2 receptors at concentrations > 40 nM. Attenuates MET...
Noscapine is often used as an antitussive medication.
Extrat from the seeds of Corchorus olitoriu, a cardiac Glycoside.
A muscarinic receptors antagonist.
Apamin is an 18 amino acid peptide toxin found in bee venom. Apamin is used to elucidate the roles of these channels in cells and tissues expressing SK channels...
Doxorubicin (Adriamycin) is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.
Diamine oxidase activator. Na+ channels blocker.
Fraxinellone is an insecticidal agent, inhibiting growth of larvae, used in the treatment and protection of crops and produce. Also, a naturally occurring compo...
Carothane complex ester , from plants of the Umbelliferae family.
Auristatin F is a cytotoxic tubulin modifier with potent and selective antitumor activity; MMAF analog and cytotoxin in Antibody-drug conjugates.