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Topotecan - CAS 123948-87-8

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Category
ADCs
Product Name
Topotecan
Synonyms
(S)-10-((dimethylamino)methyl)-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione hydrochloride;Hycamtin; SKF104864;
CAS Number
123948-87-8
Description
Topotecan has been used as a positive control for the identification and analysis of HIF-1α and VEGF inhibitors in human glioma cells under hypoxic conditions. It has also been used for in vitro apoptosis assays in PA317 cells.
Molecular Weight
421.45
Molecular Formula
C23H23N3O5
COA
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MSDS
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Canonical SMILES
CC[C@@]1(c2cc3n(c(=O)c2COC1=O)Cc4c3nc5ccc(c(c5c4)CN(C)C)O)O
InChI
InChI=1S/C23H23N3O5/c1-4-23(30)16-8-18-20-12(9-26(18)21(28)15(16)11-31-22(23)29)7-13-14(10-25(2)3)19(27)6-5-17(13)24-20/h5-8,27,30H,4,9-11H2,1-3H3/t23-/m0/s1
InChIKey
UCFGDBYHRUNTLO-QHCPKHFHSA-N
Tag
ADCs Cytotoxin
Structure
CAS 123948-87-8 Topotecan
Specification
Purity
≥95%
Appearance
Soild powder
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