(-)-THUJOPSEN - CAS 470-40-6
Category:
Main Product
Product Name:
(-)-THUJOPSEN
Catalog Number:
470-40-6
Synonyms:
(Z)-Thujopsene; 1,1a,4,4a,5,6,7,8-octahydro-2,4a,8,8-tetramethyl-cyclopropa[d]naphthalen[1; 2,4a,8,8-Tetramethyl-1,1a,4,4a,5,6,7,8-octahydrocyclopropa[d]naphthalene; 4abeta,8atheta)]-as-(1aalph; cis-(-)-Thujopsene; cis-thujopsene
CAS Number:
470-40-6
Molecular Weight:
204.35
Molecular Formula:
C15H24
Quantity:
Data not available, please inquire.
COA:
Inquire
MSDS:
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Canonical SMILES:
CC1=CCC2(CCCC(C23C1C3)(C)C)C
InChI:
InChI=1S/C15H24/c1-11-6-9-14(4)8-5-7-13(2,3)15(14)10-12(11)15/h6,12H,5,7-10H2,1-4H3/t12-,14-,15-/m0/s1
InChIKey:
WXQGPFZDVCRBME-QEJZJMRPSA-N
Chemical Structure
CAS 470-40-6 (-)-THUJOPSEN

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Reference Reading


1.Bioactive sesquiterpenes from the essential oil of Thuja orientalis.
Kim KH1, Moon E, Kim SY, Choi SU, Son MW, Choi SZ, Lee KR. Planta Med. 2013 Nov;79(17):1680-4. doi: 10.1055/s-0033-1350952. Epub 2013 Oct 17.
A phytochemical investigation on the essential oil of Thuja orientalis resulted in the isolation and identification of three new sesquiterpenes, 3α-methoxy-4α-epoxythujopsane (1), Δ³,¹⁵-4β-epoxythujopsene (2), and Δ³,⁴-thujopsen-2,15-diol (3), together with eight known sesquiterpenoids (4-11). The structures of these new compounds were elucidated based on spectroscopic data analyses including extensive 2D-NMR data and HR-ESIMS. The full assignments of ¹H and ¹³C NMR chemical shifts for thujopsadiene (4) were obtained by 2D-NMR for the first time. All compounds (1-11) showed antiproliferative activities against the SK-OV-3 and SK-MEL-2 cell lines with IC₅₀ values of 5.85-28.64 µM. In addition, compounds 1, 3, 4, 7, 8, and 9 significantly inhibited nitric oxide production in lipopolysaccharide-activated BV-2 cells with IC₅₀ values of 3.93-17.85 µM without cell toxicity.