|Description||Alkaloid, extracted from Thalictrum isopyroide.|
C19-norditerpenoid alkaloid , from plants of the Ranunculaceae family, a potent antiarrhythmic, antifibrillatory; Na+ channel blocker in cardiomyocytes.
Calciseptine is a natural neurotoxin isolated from the black mamba Dendroaspis p. polylepis venom. This toxin consists of 60 amino acids with four disulfide bon...
α-Neurotoxins from snake venoms that tightly bind nAChRs contain 60-75 amino acid (aa) residues and are linked by 4-5 disulfide bridges. an antagonist of the ni...
Taltobulin trifluoroacetate (HTI-286; SPA-110) is an analogue of Hemiasterlin; potent tubulin inhibitor; ADCs cytotoxin.
Askendoside D presents a high selectivity for the cardiac Na+/K+-ATPase, with practically no activity on brain or kidney Na+/K+-ATPases, as compared with other ...
ShK – Stichodactyla toxin
ShK (Stichodactyla helianthus Neurotoxin) has been isolated from the venom of the Carribean sea anemone Stoichactis helianthus. ShK inhibits voltage-dependent p...
Synthetic, a potent inhibitor of high-affinity choline uptake (HAChU) in synaptosomes.
Synthetic, a weak AChR antagonist.
Noscapine is often used as an antitussive medication.
M2 muscarinic receptor antagonist; myorelaxant. Steroid alkaloid derivative of Imperialine from the plant Petilium eduardi, and P. raddeanae.
Artesunate is a derivative of the natural product artemisinin which effectively kills the malarial parasites P. falciparum and P. vivax. It also kills trematode...
Ionotropic GABAA receptors are ligand-gated ion channels that facilitate the passing of chloride ions across the cell membrane and promote an inhibitory influen...
C20-diterpenoid alkaloid , from the Ranunculaceae family,an antiarrhythmic.
An inhibitor of MAO.
Atropine is a medication used to treat certain types of nerve agent and pesticide poisonings, some types of slow heart rate, and to decrease saliva production d...
Seco-Duocarmycin GA is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Ansamitocin P-3, a potent anti-tumor maytansinoid found in Actinosynnema pretiosum, is a maytansine analog which displays potent cytotoxicity against the human ...
Nemorubicin, is a doxorubicin derivative that differs significantly from its parent drug in terms of spectrum of antitumor activity, metabolism and toxicity pro...
[Tyr2]-Scyllatoxin allows labelling by iodination. 31-amino acid polypeptide with 3 disulfide bridges. , synthetic, originally from Leiurus quinquestriatus hebr...
Anti-inflammatory, antioxidant and free radical scavenger. Inhibits LPS-induced TNF-α, IL-6 and inducible nitric oxide production and blocks NF-κB and AP-1 acti...