A selective M-AChR agonist. Rigid bicyclic analog of ACh. Good penetration of biological membranes. Quinuclidine derivative , synthetic.
Tschimgine a substance presenting an estrogenic activity..
PNU-159682 is a major active metabolite of nemorubicin (MMDX) in human liver microsomes. PNU-159682 showed > 3,000-fold cytotoxic than its parent compound(MMDX ...
Syntheticquinazolone alkaloid, inhibiting cholinesterase activity in vitro.
Hydrochloride salt of DL-Tetrahydropalmatine is the main active substance of the Chinese herb corydalis which induces hypotension and bradycardia in rats throug...
an anesthetic acting on the nerve endings, with a good selectivity on sensory nerves; lowers arterial pressure; vasodilator. Tropane alkaloid , from plants of t...
Extract from roots of Aconitum piepunense. A new chemical class of ganglioblocker, myorelaxant of reversible type.
Agitoxin-2 is a potent and selective blocker of the Shaker type voltage-gated Kv1.3 and Kv1.1 channels. Agitoxin-2 inhibits Kv1.3 with an IC50 value of around 2...
Synthetic, nicotinic AChR. Rigid bicyclic analog of TMA and TEA.
Carothane complex ester , from plants of the Umbelliferae family.
Alkaloid extracted from Haplophyllum perforatum, a sedative and analgesic compound Tetrahydroquinoline
Long-acting, centrally active acetylcholinesterase inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors. Prevents β-amyloid-...
Potent inhibitor of Ca2+ release from sarcoplasmic reticulum
A selective blocker of the delayed rectifier K+ channel found in virtual screening
Extracted from Haplophyllum perforatum plant (Rutaceae fam.). An antiarrhythmic of first class Quinoline alkaloid
Monomethyl auristatin D Hcl (MMAD Hcl), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate.
Conantokin-G is a conopeptide that has been isolated from the venom of the cone Conus geographus. Conantokin-G selectively inhibits NR2B containing N-methyl-D-a...
ω-agatoxin-IVA (ω-AGA IVA) is a peptide originally isolated from funnel web-spider venom Agelenopsis aperta. This peptide is a specific blocker of P/Q-type calc...
Aconitine (AC), an active/toxic alkaloid from Aconitum species, is commonly present in Traditional Chinese Medicine (TCM) prescriptions because of the great eff...
organophosphoric inhibitor, SA-152, on the fibrinogen-coagulating and TAME-esterase activity of bovine α-thrombin.