TTX is a potent marine-derived neurotoxin that reversibly inhibits the inward sodium current through voltage-activated sodium (NaV) channels, blocking nerve and...
Hydrastine is a natural alkaloid which is present in Hydrastis canadensis and other plants of the ranunculaceae family.
Lignan , from plants of the Rutaceae family, a substance presenting an estrogenic activity and sedative effects. .
Tubulysin A is a novel antibiotic, which is anti-microtubule, anti-mitotic, apoptosis inducer, anticancer, anti-angiogenic, and antiproliferative. Tubulysins sh...
Microcystin-RR inhibits PP1C, PP1γ, and PP2A with Ki values of 0.15, 0.24, and 0.018 nM, respectively.
Bicyclic analog of Ach, a weak muscarinic AChR agonist.
Hydrobromide salt of (+)-Lappaconitine, a potential antitumor agent agent that induces HL-60 differentiation and apoptosis with analgesic activity as well.
Diazoxide is a potassium channel activator that causes local relaxation in smooth muscle by increasing membrane permeability to potassium ions. The cellular rel...
β-Bungarotoxin is a form of bungarotoxin that is fairly common in Krait (Bungaros multicinctus) venoms. A pre-synaptic toxin with enzymatic activity.
Monomethyl auristatin D (MMAD), a potent tubulin inhibitor, is a toxin payload and antibody drug conjugate.
Iron carrier Synthetic
Mesaconitine has antinociceptive activity through cyclic AMP and stimulation of the central β-adrenergic system.
Trichodesmine is a pyrrolizidine alkaloid that has neurotoxic effects and is naturally found in Crotolaria argyptiaca, a shrub plant that is native to the south...
Nitrodienamine, an inhibitor of Ca2+/Mg2+ ATPase.
A spasmolytic agent, shows pharmacol. props. similar to 2-(Methylamino)-1-phenyl-1-propanol BCJ45-G.
α-Dendrotoxin inhibits 4-AP sensitive, inactivating voltage-gated<br/>K+ channels (KV1.1, KV1.2 and KV1.6).
A highly active peripheral M2-cholinoblocker alkaloid. Cervane alkaloid derivative of Imperialine from the plant Petilium eduardi.
Cyclopiazonic acid is a mycotoxin produced by molds including certain species of Penicillium and Aspergillus. Its toxicity is linked to its ability to specifica...
Tetrahydroberberine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Tetrahydroberber...
DM4 is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates.