|Description||Synthetic, GABAA-gated Cl- channels blocker; non-competitive GABAA antagonist.|
Idarubicin is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells with IC50 of 3.3 ng/mL.
Ruthenium red is a polycationic dye that inhibits sarcoplasmic reticulum Ca2+ release, blocks Ca2+ uptake and release from mitochondria, and prevents Ca2+ relea...
Seco-Duocarmycin GA is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Antiarrhythmic and hypotensive; ganglion blocker; exhibits weak affinity at brain α-bungarotoxin-sensitive nicotinic acetylcholine receptors.
Extract from plants of the Heliotropum genus, an alkaloid used for obtaining models of hepatitis and cirrhosis of the liver.
A selective inhibitor of endoplasmic reticulum Ca2+-ATPase.
Synthetic, nicotinic AChR. Rigid bicyclic analog of TMA and TEA.
Hyoscyamine is a tropane alkaloid. It is a secondary metabolite found in certain plants of the family Solanaceae, non-selective antagonist at Muscarinic recepto...
Tubulysin A is a novel antibiotic, which is anti-microtubule, anti-mitotic, apoptosis inducer, anticancer, anti-angiogenic, and antiproliferative. Tubulysins sh...
Methimazole inhibits the enzyme thyroperoxidase, which normally acts in thyroid hormone synthesis by oxidizing the anion iodide (I−) to iodine (I2), hypoiodous ...
Quinoline alkaloid, extracted from Haplophyllum bucharicum (Rutacae)
Tubulysin B is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
A neuronal nicotinic AChR antagonist, blocking superior cervical sympathetic ganglion
A potent non-competitive GABA antagonist in mammalian, molluscan and insects; convulsant;laboratory insecticide.
An activator of voltage-sensitive Na+ channels, a suite of cyclic polyether compounds produced naturally by a species of dinoflagellate known as Karenia brevis....
anti-hypoxic; acts on the mitochondrial respiratory chain; prevents atherosclerosis; angioprotector. Sum of polymerized Proantocyanides , from the plants of Fab...
β-Pompilidotoxin slows the inactivation of neuronal Navs. β-Pompilidotoxin was isolated from the venoms of two wasps, Anoplius amariensis and Batozonellus macul...
A cytolytic toxin that causes depolarization of skeletal muscle fibers in vitro. Stimulates Ca2+ transport and ATP hydrolysis by the sarcolemmal Ca2+/Mg2+-ATPas...
Solasodine(Purapuridine) is a poisonous alkaloid chemical compound that occurs in plants of the Solanaceae family. Solasodine showed selective cytotoxicity agai...
C20-diterpenoid alkaloid , from the Ranunculaceae family,an antiarrhythmic.