|Description||Tetrodotoxin, frequently abbreviated as TTX, is a potent neurotoxin. Its name derives from Tetraodontiformes, an order that includes pufferfish, porcupinefish, ocean sunfish or mola, and triggerfish; several species that carry the toxin. Although tetrodotoxin was discovered in these fish and found in several other animals (e.g., blue-ringed octopus, rough-skinned newt, and Naticidae) it is actually produced by certain symbiotic bacteria, such as Pseudoalteromonas tetraodonis, certain species of Pseudomonas and Vibrio, as well as some others that reside within these animals. Tetrodotoxin inhibits the firing of action potentials in nerves by binding to the voltage-gated sodium channels in nerve cell membranes and blocking the passage of sodium ions (responsible for the rising phase of an action potential) into the nerve cell.|
|Quality Standard||Enterprise Standard|
|COA||Certificate of Analysis-Tetrodotoxin 4368-28-9 B15J0509|
This active molecular is a human Nav1.7 voltage gated sodium channel inhibitor with the IC50 value of 28 nM. PF-04856264 inhibits the Nav channel by interacting...
(-)-Sparteine sulfate pentahydrate
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Dibucaine HCl is a local anesthetics.Among the most potent and toxic of the long-acting local anesthetics, current use of it is generally restricted to spinal a...
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