Monomethyl auristatin D Hcl (MMAD Hcl), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate.
An activator of voltage-sensitive Na+ channels, a suite of cyclic polyether compounds produced naturally by a species of dinoflagellate known as Karenia brevis....
Seco-Duocarmycin MB is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Fraxinellone is an insecticidal agent, inhibiting growth of larvae, used in the treatment and protection of crops and produce. Also, a naturally occurring compo...
Extractedfrom Vinca erecta. A dopamine receptor stimulating agent Indolinine alkaloid
Solasodine(Purapuridine) is a poisonous alkaloid chemical compound that occurs in plants of the Solanaceae family. Solasodine showed selective cytotoxicity agai...
Carothane complex ester , from plants of the Umbelliferae family.
A selective blocker of the delayed rectifier K+ channel found in virtual screening
Tubulysin A is a novel antibiotic, which is anti-microtubule, anti-mitotic, apoptosis inducer, anticancer, anti-angiogenic, and antiproliferative. Tubulysins sh...
A proanthocyanidin from Polygonum coriaricum, an antihypoxic.
Taltobulin, also known as HTI-286 and SPA-110, is a fully synthetic analog of the natural tripeptide hemiasterlin, inhibits tubulin polymerization and circumven...
Chlorotoxin (Cltx) is a neurotoxin that was originally isolated from the venom of Leiurus quinquestriatus. Chlorotoxin is a specific ligand of glioma cells. Chl...
an anesthetic acting on the nerve endings, with a good selectivity on sensory nerves; lowers arterial pressure; vasodilator. Tropane alkaloid , from plants of t...
Nitrodienamine, an inhibitor of Ca2+/Mg2+ ATPase.
Methotrexate(WR19039; CL14377) can interfere with the growth of certain cells of the body, especially cells that reproduce quickly, such as cancer cells, bone m...
A potent antiarrhytmic and local anesthetic. Alkaloid , from plants of the Ranunculaceae family. Inhibitorand Enhancers of Uridine Diphosphate-Glucuronosyltrans...
An inhibitor of serine proteinases of broad spectrum.
Potent antagonist for α7-containing neuronal nicotinic receptors (Ki = 1.4 nM). Interacts with α4β2 and α6β2 receptors at concentrations > 40 nM. Attenuates MET...
A microtubule-disrupting agent.