7-Epi 10-Desacetyl Paclitaxel
7-Epi 10-Desacetyl Paclitaxel is a derivative of Paclitaxel, which is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells.
PNU-159682 is a major active metabolite of nemorubicin (MMDX) in human liver microsomes. PNU-159682 showed > 3,000-fold cytotoxic than its parent compound(MMDX ...
Duocarmycin SA is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
20-Hydroxyecdysone (ecdysterone or 20E) is a naturally occurring ecdysteroid hormone which controls the ecdysis (moulting) and metamorphosis of arthropods. It i...
Synthetic, a potent inhibitor of high-affinity choline uptake (HAChU) in synaptosomes.
Synthetic, a neuronal nicotinic AChR antagonist.
Quinoline alkaloid, extracted from Haplophyllum bucharicum (Rutacae)
Taltobulin, also known as HTI-286 and SPA-110, is a fully synthetic analog of the natural tripeptide hemiasterlin, inhibits tubulin polymerization and circumven...
Diplacine is a nicotinic cholinoreceptor antagonist at the neuromuscular junction.
Melamine is a widely used, broad-spectrum benzimidazole fungicide and a metabolite of benomyl. It is also employed as a casting worm control agent in amenity tu...
10-Deacetyl-7-xylosyl paclitaxel is a Paclitaxel derivative with improved pharmacological features and higher water solubility.
Artemether is an antimalarial for the treatment of multiple drug-resistant strains of Plasmodium falciparum malaria.
Norfluorocurarine is a peripheral vasodilator that increases blood flow to the brain (sold under the trademark Oxybral SR) .<br/>Generic drugs containing vincam...
Morphiceptin is a four amino acid peptide derived from the ß-casomorphin, a protein fragment itself derived from the digestion of milk protein casein. It is one...
A neuronal nicotinic AChR antagonist, blocking superior cervical sympathetic ganglion
Calicheamicin is a potent DNA-binding cytotoxic antibiotic.Calicheamicin being the most notable enediyne antitumor antibiotics derived from the bacterium Microm...
Mesaconitine has antinociceptive activity through cyclic AMP and stimulation of the central β-adrenergic system.
Ionotropic GABAA receptors are ligand-gated ion channels that facilitate the passing of chloride ions across the cell membrane and promote an inhibitory influen...
a non specific stimulant of immunogenesis; also used for erytrocytes hemolysis and automatic leucocyte numbering. Triterpene saponine, mixture of 4 glycosides f...
Long-acting, centrally active acetylcholinesterase inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors. Prevents β-amyloid-...