an antagonist of the nicotinic acetylcholine receptor at the neuromuscular junction. Erabutoxin B from Laticauda semifasciata (Sea Snake)
Nitrodienamine, an inhibitor of Ca2+/Mg2+ ATPase.
Potent ganglioblocker, a neuronal nicotinic AChR antagonist. .
Brevetoxin B is a polyketide neurotoxin produced by Karenia species and other dinoflagellates. It binds to site 5 on the alpha subunit of voltage-gated sodium c...
Protopine is a benzylisoquinoline alkaloid occurring in opium poppy, Corydalis tubers and other plants of the family papaveraceae, like Fumaria officinalis. It ...
Ca2+-Activated K+ Channel Blocker
Combretastatin A4, under the IUPAC name 2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol, inhibits tubulin polymerization (IC50= 2.2 μM). It has demons...
Triptolide is a diterpene triepoxide, immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii.
An ATPase inhibitor.
A Na+ channel blocker; potent antiarrhythmic, inhibits voltage-gated Na+ channels in rat brain synaptosomes.
Is any neutral chemical compound with a positively charged cationic functional group such as a quaternary ammonium or phosphonium cation which bears no hydrogen...
Paclitaxel is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells.
Anhydroperforine from the seeds of Haplophyllum perforatum.
DM1 is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates.
Delsoline is a hypotensive alkaloid isolated from Aconitum.
A scorpion alpha-insect toxin, which prolongs the evoked action potential by an inhibition of sodium current inactivation in insects and mammals.
A spasmolytic agent, shows pharmacol. props. similar to 2-(Methylamino)-1-phenyl-1-propanol BCJ45-G.
Potent inhibitor of Ca2+ release from sarcoplasmic reticulum
Synthetic, GABAA-gated Cl- channels blocker; non-competitive GABAA antagonist.
A microtubule-disrupting agent.