|Description||Taltobulin, also known as HTI-286 and SPA-110, is a fully synthetic analog of the natural tripeptide hemiasterlin, inhibits tubulin polymerization and circumvents transport-based resistance to taxanes. HTI-286 was a potent inhibitor of proliferation (mean IC50 = 2.5 Â± 2.1 nm in 18 human tumor cell lines) and had substantially less interaction with multidrug resistance protein (P-glycoprotein) than currently used antimicrotubule agents, including paclitaxel, docetaxel, vinorelbine, or vinblastine.|
An antineoplastic alkaloid from Colchicum autumnale L. isolated from Colchicum autumnale L.
Extractedfrom Vinca erecta. A dopamine receptor stimulating agent Indolinine alkaloid
An anesthetic acting on the nerve endings, with a good selectivity on sensory nerves; lowers arterial pressure; vasodilator. Tropane alkaloid , from plants of t...
Lqh alpha IT Recombinant
A scorpion alpha-insect toxin, which prolongs the evoked action potential by an inhibition of sodium current inactivation in insects and mammals.
Microcystin-RR inhibits PP1C, PP1γ, and PP2A with Ki values of 0.15, 0.24, and 0.018 nM, respectively.
Extract from plants of the Heliotropum genus, an alkaloid used for obtaining models of hepatitis and cirrhosis of the liver.
Rutin is colored brown by tobacco enzyme under experimental conditions
Synthetic, nicotinic AChR. Rigid bicyclic analog of TMA and TEA.
Tubulysin A is a novel antibiotic, which is anti-microtubule, anti-mitotic, apoptosis inducer, anticancer, anti-angiogenic, and antiproliferative. Tubulysins sh...
Ca2+-Activated K+ Channel Blocker
A muscarinic receptors antagonist.
A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and ...
DM3 is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates.
Fraxinellone is an insecticidal agent, inhibiting growth of larvae, used in the treatment and protection of crops and produce. Also, a naturally occurring compo...
Cloflubicyne is a potent non-competitive GABA antagonist, convulsant, laboratory insecticide.
Psoralen is a photoactive probe that has been used to investigate nucleic acid structure and function. It intercalates into DNA and, when activated by ultraviol...
Iron carrier Synthetic
Muscarinic toxin 2 (MT2) is one member of a family of small peptides of 65 amino acid residues of around 7076 daltons in molecular weight derived from the venom...
Sanguinarine is a toxic quaternary ammonium salt from the group of benzophenanthridine alkaloids. It is extracted from some plants, including bloodroot (Sanguin...
Alkaloid, extracted from Thalictrum isopyroide.