Taltobulin - CAS 228266-40-8
Not Intended for Therapeutic Use. For research use only.
Category:
ADCs
Product Name:
Taltobulin
Catalog Number:
228266-40-8
CAS Number:
228266-40-8
Description:
Taltobulin, also known as HTI-286 and SPA-110, is a fully synthetic analog of the natural tripeptide hemiasterlin, inhibits tubulin polymerization and circumvents transport-based resistance to taxanes. HTI-286 was a potent inhibitor of proliferation (mean IC50 = 2.5 ± 2.1 nm in 18 human tumor cell lines) and had substantially less interaction with multidrug resistance protein (P-glycoprotein) than currently used antimicrotubule agents, including paclitaxel, docetaxel, vinorelbine, or vinblastine.
Molecular Weight:
473.32
Molecular Formula:
C27H43N3O4
COA:
Inquire
MSDS:
Inquire
Tag:
ADCs Cytotoxin
Chemical Structure
CAS 228266-40-8 Taltobulin

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