Auristatin F is a cytotoxic tubulin modifier with potent and selective antitumor activity; MMAF analog and cytotoxin in Antibody-drug conjugates.
A potent non-competitive GABA antagonist in mammalian, molluscan and insects; convulsant;laboratory insecticide.
Quinoline alkaloid, extracted from Haplophyllum bucharicum (Rutacae)
Synthetic, nicotinic AChR. Rigid bicyclic analog of TMA and TEA.
A Na+ channel blocker; potent antiarrhythmic, inhibits voltage-gated Na+ channels in rat brain synaptosomes.
Tubulysin M is a Tubulysin D analog with potential anti-cancer properties, used as the cytotoxic component in antibody-drug conjugates.
Ryanodine High Purity
Potent inhibitor of Ca2+ release from sarcoplasmic reticulum
A methyl easter of Okadaic acid. Okadaic acid is a marine sponge toxin which potently inhibits certain serine/threonine protein phosphatases.
Terpenoids found in the umbelliferae family act as agonists/antagonists for ER(alpha) and Erbeta.
Margatoxin (MgTx) is a component of the venom of Scorpio Centruroides margaritatus. Margatoxin preferentially inhibits voltage-dependent potassium channels Kv1....
Conantokin-G is a conopeptide that has been isolated from the venom of the cone Conus geographus. Conantokin-G selectively inhibits NR2B containing N-methyl-D-a...
β-Bungarotoxin is a form of bungarotoxin that is fairly common in Krait (Bungaros multicinctus) venoms. A pre-synaptic toxin with enzymatic activity.
A native alkaloid A tropane alkaloid Extracted from Convolvulus subhirsitus plant.
Bicyclic analog of Ach, a weak muscarinic AChR agonist.
Tschimgine a substance presenting an estrogenic activity..
Anticoagulant: irreversible inhibits serine proteinase a-thrombine. Fluorocontaining phosphonate, synthetised.
A selective inhibitor of endoplasmic reticulum Ca2+-ATPase.
Chlorotoxin (Cltx) is a neurotoxin that was originally isolated from the venom of Leiurus quinquestriatus. Chlorotoxin is a specific ligand of glioma cells. Chl...
Topotecan has been used as a positive control for the identification and analysis of HIF-1α and VEGF inhibitors in human glioma cells under hypoxic conditions. ...
An anesthetic acting on the nerve endings, with a good selectivity on sensory nerves; lowers arterial pressure; vasodilator. Tropane alkaloid , from plants of t...