Microcystin-RR inhibits PP1C, PP1γ, and PP2A with Ki values of 0.15, 0.24, and 0.018 nM, respectively.
Alkaloid extracted from Haplophyllum perforatum, a sedative and analgesic compound Tetrahydroquinoline
Ca2+-Activated K+ Channel Blocker
Ruthenium red is a polycationic dye that inhibits sarcoplasmic reticulum Ca2+ release, blocks Ca2+ uptake and release from mitochondria, and prevents Ca2+ relea...
Nitrodienamine, an inhibitor of Ca2+/Mg2+ ATPase.
Potent inhibitor of protein phosphatase tyoe 1 (PP1) and protein phosphatase tyoe 2A (PP2A).
Tubulysin B is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Synthetic, a selective irreversible inhibitor of carboxylesterases
10-Deacetyl-7-xylosyl paclitaxel is a Paclitaxel derivative with improved pharmacological features and higher water solubility.
Lycoctonine is a plant alkaloid and a precursor to the ABC ring system of taxoids.
Potent blocker of voltage-sensitive K+ channels (IC50 values are 0.1, 1.1 and 25 nM for KV1.3, KV1.1 and KV1.2 channels) respectively). Also inhibits Ca2+-activ...
β-Bungarotoxin is a form of bungarotoxin that is fairly common in Krait (Bungaros multicinctus) venoms. A pre-synaptic toxin with enzymatic activity.
Mitomycin C is a DNA crosslinking agent that inhibits DNA synthesis and induces apoptosis in a variety of cells.
M2 muscarinic receptor antagonist; myorelaxant. Steroid alkaloid derivative of Imperialine from the plant Petilium eduardi, and P. raddeanae.
7-Epi 10-Desacetyl Paclitaxel
7-Epi 10-Desacetyl Paclitaxel is a derivative of Paclitaxel, which is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells.
An inhibitor of MAO.
Etbicuphat is a GABAa receptor antagonist known to cause convulsions, seizures and other neuromuscular related episodes. Used in the study of anti-epileptic dru...
Steroidal Alkaloid from Convolvulus krauseanus
TTX is a potent marine-derived neurotoxin that reversibly inhibits the inward sodium current through voltage-activated sodium (NaV) channels, blocking nerve and...
Cynaroside is a flavone, a flavonoid-like chemical compound. It is a 7-O-glucoside of luteolin.