Syntheticquinazolone alkaloid, inhibiting cholinesterase activity in vitro.
Camptothecin (CPT) is a potent DNA enzyme topoisomerase I (topo I) inhibitor with an IC50 and IC70 of 50 nM and 0.225 μM for breast cancer cell line MDA-MB-231.
Lycorine is a toxic crystalline alkaloid found in various Amaryllidaceae species, such as the cultivated bush lily , surprise lilies, and daffodils. It may be h...
Aconitine (AC), an active/toxic alkaloid from Aconitum species, is commonly present in Traditional Chinese Medicine (TCM) prescriptions because of the great eff...
Diazoline is used for symptomatic relief of allergic symptoms caused by histamine release, including nasal allergies and allergic dermatosis.
Calicheamicin is a potent DNA-binding cytotoxic antibiotic.Calicheamicin being the most notable enediyne antitumor antibiotics derived from the bacterium Microm...
Phencarol is used in the biological studies of azoniabicyclooctanes as muscarinic acetylcholine receptor antagonists.
An activator of voltage-sensitive Na+ channels, a suite of cyclic polyether compounds produced naturally by a species of dinoflagellate known as Karenia brevis....
α-Cobratoxin is a substance of the venom of certain Naja cobras. It is a nicotinic acetylcholine receptor (nAChR) antagonist which causes paralysis by preventin...
Triptolide is a diterpene triepoxide, immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii.
Diterpenoid , from plants of the Stevia genus, Compositae. Sweetener; reported as possessing anti-hypertensive effects upon hypertensive rats.
Potent, cell-permeable, IP3-independent intracellular calcium releaser. Blocks the transient increase in intracellular Ca2+ induced by angiostatin and endostati...
Muscarinic toxin 2
Muscarinic toxin 2 (MT2) is one member of a family of small peptides of 65 amino acid residues of around 7076 daltons in molecular weight derived from the venom...
An inhibitor of MAO.
Dantrolene sodium is a postsynaptic muscle relaxant that lessens excitation-contraction coupling in muscle cells. It achieves this by inhibiting Ca2+ ions relea...
Artesunate is a derivative of the natural product artemisinin which effectively kills the malarial parasites P. falciparum and P. vivax. It also kills trematode...
An antiarrhythmic of 1-st and 1Y classes and a blocker of TTX sensitive Na+ channels, Ca++ antagonist diterpene alkaloid from Delphinium staphisagria.
an anesthetic acting on the nerve endings, with a good selectivity on sensory nerves; lowers arterial pressure; vasodilator. Tropane alkaloid , from plants of t...
Maitansine, a cytotoxic agent, inhibits the assembly of microtubules by binding to tubulin at the rhizoxin binding site.
Alkaloid , from plants of the Ungernia genus, Amaryllidaceae.