Melittin inhibits protein kinase C, Ca2+/calmodulin-dependent protein kinase II, myosin light chain kinase and Na+/K+-ATPase (synaptosomal membrane) and is a ce...
hypotensive, central adrenolytic Semisynthetic derivative of natural alkaloid Galantamine Extracted from Ungernia Victoris (Amarillidaceae Fam.)
Alkaloid from reticuline and is a precursor of berberine.It has also been found to be a GABAA receptor agonist.
A selective M-AChR agonist. Rigid bicyclic analog of ACh. Good penetration of biological membranes. Quinuclidine derivative , synthetic.
Anti-inflammatory, antioxidant and free radical scavenger. Inhibits LPS-induced TNF-α, IL-6 and inducible nitric oxide production and blocks NF-κB and AP-1 acti...
Duocarmycin SA is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Ansamitocin P-3, a potent anti-tumor maytansinoid found in Actinosynnema pretiosum, is a maytansine analog which displays potent cytotoxicity against the human ...
Hydrochloride salt of DL-Tetrahydropalmatine is the main active substance of the Chinese herb corydalis which induces hypotension and bradycardia in rats throug...
Imperialine is an isosteroidal alkaloid from Fritillaria thunbergii, a short-acting selective M2 muscarinic receptor antagonist.
A Na+ channel blocker; potent antiarrhythmic, inhibits voltage-gated Na+ channels in rat brain synaptosomes.
ω-conotoxin MVIIC (omega conotoxin MVIIC) is a conotoxin that has been isolated from the venom of the cone Conus magus. ω-conotoxin MVIIC is a blocker of P/Q an...
Imperatoxin is a peptide toxin derived from the venom of the African scorpion Pandinus imperator. an inhibitor of Ca2+-release channels from sarcoplasmic reticu...
Anticoagulant: irreversible inhibitor of serine proteinase a-thrombine. Fluorocontaining phosphonate, identifies an inflammatory subpopulation of macrophages in...
Norfluorocurarine is a peripheral vasodilator that increases blood flow to the brain (sold under the trademark Oxybral SR) .<br/>Generic drugs containing vincam...
Triptolide is a diterpene triepoxide, immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii.
Irofulven is a semisynthetic sesquiterpene derivative of illudin S, a natural toxin isolated from the fungus Omphalotus illudens. Irofulven alkylates DNA and pr...
Synthetic, a selective irreversible inhibitor of carboxylesterases
An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin.
Agitoxin-2 is a potent and selective blocker of the Shaker type voltage-gated Kv1.3 and Kv1.1 channels. Agitoxin-2 inhibits Kv1.3 with an IC50 value of around 2...
22-amino acid peptide with a strongly basic character and 2 disulfide bridges, , from Apis mellifera bee venom, a blocker of voltage-sensitive K+ channels with ...