|Description||Seco-Duocarmycin DMG is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.|
Alkaloid , from plants of the Ungernia genus, Amaryllidaceae.
Tropane alkaloid, from plants of the Convolvulus genus,
A potent antiarrhytmic and local anesthetic. Alkaloid , from plants of the Ranunculaceae family. Inhibitorand Enhancers of Uridine Diphosphate-Glucuronosyltrans...
Idarubicin is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells with IC50 of 3.3 ng/mL.
An ATPase inhibitor.
A selective inhibitor of endoplasmic reticulum Ca2+-ATPase.
Mebicyphat is shown to be a non-competitive GABA antagonist. Blocks GABA gated Cl- channels, and is shown to inhibit dihydropicrotoxin
Nitrodienamine, an inhibitor of Ca2+/Mg2+ ATPase.
Unsevine acts directly on the CNS, inhibits the reaction of orientation, prolongs the action of soporifics, enhances the effects of analgesics and prevents conv...
Gramine is a naturally occurring indole alkaloid present in several plant species. Gramine may play a defensive role in these plants, since it is toxic to many ...
An analog of Veratridine; Na+ channel activator; potent neurotoxic; depolarizing agent on membranes of nerve terminal, muscle and gland cells.
Synthetic, a potent inhibitor of high-affinity choline uptake (HAChU) in synaptosomes.
Antiarrhythmic and hypotensive; ganglion blocker; exhibits weak affinity at brain α-bungarotoxin-sensitive nicotinic acetylcholine receptors.
Derivative of Napelline. Napelline isolated from plant Aconitum karakolicum Diterpenoid Alkaloid Synthesized from Napelline. Napelline is extracted from Aconitu...
Steroidal Alkaloid from Convolvulus krauseanus
Potent, cell-permeable, IP3-independent intracellular calcium releaser. Blocks the transient increase in intracellular Ca2+ induced by angiostatin and endostati...
Microcystin-LR is a selective inhibitor of protein phosphatase 2A (PP2A) (IC50= 0.04 nM) and will completely inhibit this enzyme without affecting PP1 when used...
Cervane alkaloid derivative of Imperialine from the plant Petilium eduardi. A selective M2 muscarinic receptor antagonist.
Ionotropic GABAA receptors are ligand-gated ion channels that facilitate the passing of chloride ions across the cell membrane and promote an inhibitory influen...
PBD dimer is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.