|Product Name||Seco-Duocarmycin TM|
|Description||Seco-Duocarmycin TM is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.|
Combretastatin A4, under the IUPAC name 2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol, inhibits tubulin polymerization (IC50= 2.2 μM). It has demons...
Topotecan has been used as a positive control for the identification and analysis of HIF-1α and VEGF inhibitors in human glioma cells under hypoxic conditions. ...
Triptolide is a diterpene triepoxide, immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii.
An antineoplastic alkaloid from Colchicum autumnale L. isolated from Colchicum autumnale L.
β-Bungarotoxin is a form of bungarotoxin that is fairly common in Krait (Bungaros multicinctus) venoms. A pre-synaptic toxin with enzymatic activity.
Antiarrhythmic and hypotensive; ganglion blocker; exhibits weak affinity at brain α-bungarotoxin-sensitive nicotinic acetylcholine receptors.
M2 muscarinic receptor antagonist; myorelaxant. Steroid alkaloid derivative of Imperialine from the plant Petilium eduardi, and P. raddeanae.
Apamin is an 18 amino acid peptide toxin found in bee venom. Apamin is used to elucidate the roles of these channels in cells and tissues expressing SK channels...
A cytostatic substance Isotryptamine.
Alkaloid, Tetrahydroisoquinoline, Active dopamine metabolite, Cholinesterase inhibitor
ω-conotoxin MVIIC (omega conotoxin MVIIC) is a conotoxin that has been isolated from the venom of the cone Conus magus. ω-conotoxin MVIIC is a blocker of P/Q an...
Anti-inflammatory, antioxidant and free radical scavenger. Inhibits LPS-induced TNF-α, IL-6 and inducible nitric oxide production and blocks NF-κB and AP-1 acti...
A scorpion alpha-insect toxin, which prolongs the evoked action potential by an inhibition of sodium current inactivation in insects and mammals.
Amaryllidaceae alkaloid from plants of the Amaryllidaceae family. A hypotensive, sedative. Amaryllidaceae alkaloid , from plants of the Amaryllidaceae family.
Melittin inhibits protein kinase C, Ca2+/calmodulin-dependent protein kinase II, myosin light chain kinase and Na+/K+-ATPase (synaptosomal membrane) and is a ce...
Monomethylauristatin F Hcl(MMAF Hcl) is an antitubulin agent that inhibit cell division by blocking the polymerization of tubulin; lower cytotoxic activity than...
Sesquiterpene lactone , from plants of the Compositae family, an antiatherosclerotic, angioprotective, hypolipidemic and anti-inflammatory.
A highly active peripheral M2-cholinoblocker alkaloid. Imperialine is extracted from Petilium eduardi and Petilium raddeanae (Liliaceae family)
Synthetic, an inhibitor of monoamine oxydase.
Nudicauline is extracted from plants of the Ranunculaceae family, a Alpha-Bungarotoxin neuronal nicotinic receptor.