(S)-Willardiine - CAS 21416-43-3
Not Intended for Therapeutic Use. For research use only.
Category:
Inhibitor
Product Name:
(S)-Willardiine
Catalog Number:
21416-43-3
Synonyms:
(-)-Willardiine
CAS Number:
21416-43-3
Description:
The (S)- but not (R)-isomers of willardiine and 5-bromowillardiine were potent agonists, producing rapidly but incompletely desensitizing responses. At a concentration of 1.8 mM, Ca2+ inhibited the currents induced by 100 microM willardiine by approximately 50%. In newborn mice (P5, histopathology at P10), local injection of the AMPA receptor agonist S-bromo-willardiine at day 5 after birth induced cortical damage and white matter damage, which was reduced in a dose-dependent manner by the AMPA receptor antagonists.
Molecular Weight:
199.16
Molecular Formula:
C7H9N3O4
COA:
Inquire
MSDS:
Inquire
Targets:
AMPAR
Chemical Structure
CAS 21416-43-3 (S)-Willardiine

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