(S)-Gossypol acetic acid - CAS 1189561-66-7
Not Intended for Therapeutic Use. For research use only.
Category:
Inhibitor
Product Name:
(S)-Gossypol acetic acid
Catalog Number:
1189561-66-7
Synonyms:
(S)-(+)-Gossypol acetic acid
CAS Number:
1189561-66-7
Description:
(S)-Gossypol acetic acid, a Bcl-2 inhibitor, could effectively induce the death of Jurkat cells in which Bcl-2 or Bcl-xL is overexpressed. IC50: 18.1μM and 22.9μM for Bcl-2 and Bcl-xL respectively.
Molecular Weight:
578.61
Molecular Formula:
C32H34O10
Quantity:
Milligrams-Grams
COA:
Inquire
MSDS:
Inquire
Canonical SMILES:
CC1=C(C(=C2C(=C1)C(=C(C(=C2C=O)O)O)C(C)C)O)C3=C(C=C4C(=C3O)C(=C(C(=C4C(C)C)O)O)C=O)C.CC(=O)O
InChI:
InChI=1S/C30H30O8.C2H4O2/c1-11(2)19-15-7-13(5)21(27(35)23(15)17(9-31)25(33)29(19)37)22-14(6)8-16-20(12(3)4)30(38)26(34)18(10-32)24(16)28(22)36;1-2(3)4/h7-12,33-38H,1-6H3;1H3,(H,3,4)
InChIKey:
NIOHNDKHQHVLKA-UHFFFAOYSA-N
Targets:
Bcl-2 Family

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