|Synonyms||BMS-442606; 8-Azaspiro(4.5)decane-7,9-dione, 6-hydroxy-8-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)-, (6S)-;|
|Description||(S)-6-Hydroxybuspirone is a major active metabolite of Buspirone. (R)-Enantiomer showed higher affinity and selectivity for the 5HT1A receptor compared to the (S)-enantiomer; while (S)-Enantiomer has advantage of being cleared more slowly from blood compared to the (R)-enantiomer|
|Quality Standard||Enterprise standard|
|Current Developer||Bristol-Myers Squibb|
Harmine induces apoptosis and inhibits proliferation, migration and invasion of human gastric cancer cells, which may be mediated by down-regulation of COX-2 ex...
Citalopram Hydrobromide is an inhibitor of serotonin (5-HT) uptake used as an antidepressant.
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Alosetron, an effective 5-HT3 receptor antagonist, could be commonly used against irritable bowel syndrome.
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Vilazodone is a serotonin 5-HT1A partial agonist and serotonin-selective reuptake inhibitor (SPARI) that is used clinically as an antidepressant for major depre...
Ziprasidone hydrochloride monohydrate
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Clomipramine HCl is a hydrochloride salt of clomipramine which is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) bl...