Rizatriptan - CAS 144034-80-0
Category:
APIs
Product Name:
Rizatriptan
Catalog Number:
144034-80-0
CAS Number:
144034-80-0
Molecular Weight:
269.34
Molecular Formula:
C15H19N5
Quality Standard:
-
COA:
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MSDS:
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Chemical Structure
CAS 144034-80-0 Rizatriptan

Reference Reading


1. Micelle promoted multicomponent synthesis of 3-amino alkylated indoles via a Mannich-type reaction in water
Atul Kumar,* Maneesh Kumar Gupta, Mukesh Kumar and Deepti Saxena. RSC Adv., 2013, 3, 1673–1678
Theindolenucleus is an important structural unit that is present in a number of drugs currently on the market. Most of these belong to the 3-substituted indole family, which is an important intermediate for chemical synthesis and widely distributed in many important natural products. Besides, this 3-substituted indole is also an important class of pharmacophores having many biological activities i.e. Sumatriptan, Frovatriptan, Zolmitriptan and Rizatriptan are used for migraine headaches, whereas azolylbenzyl indole and bis-indole are used as a breast cancer and HIV-1 integrase inhibitor, respectively.