Hydrochloride salt of DL-Tetrahydropalmatine is the main active substance of the Chinese herb corydalis which induces hypotension and bradycardia in rats throug...
A neuronal nicotinic AChR antagonist, blocking superior cervical sympathetic ganglion
Quinoline alkaloid, extracted from Haplophyllum bucharicum (Rutacae)
Melamine is a widely used, broad-spectrum benzimidazole fungicide and a metabolite of benomyl. It is also employed as a casting worm control agent in amenity tu...
Synthetic, a potent inhibitor of high-affinity choline uptake (HAChU) in synaptosomes.
Aporphin alkaloid derivative of Isocorydine from plants of the Corydalis genus, Fumariaceae, a long-lasting ganglioblocker, with a sympathetic/parasympathetic a...
Sesquiterpene lactone , from plants of the Compositae family, an antiatherosclerotic, angioprotective, hypolipidemic and anti-inflammatory.
Monomethyl Auristatin E (MMAE) is a synthetic analog of dolastatin 10 that similarly inhibits tubulin polymerization and exhibits potent cytotoxicity. It is com...
Alkaloid extracted from Haplophyllum perforatum, a sedative and analgesic compound Tetrahydroquinoline
α-Neurotoxins from snake venoms that tightly bind nAChRs contain 60-75 amino acid (aa) residues and are linked by 4-5 disulfide bridges. an antagonist of the ni...
Extract from plants of the Leguminosae family, an antiatherosclerotic and angioprotective, reduces platelet aggregation.
Monomethyl auristatin F (MMAF) is a synthetic antineoplastic agent. It is part of some experimental anti-cancer antibody-drug conjugates such as vorsetuzumab ma...
Graveoline isolated from ethanolic extract of Ruta graveolens triggers apoptosis and autophagy in skin melanoma cells: a novel apoptosis-independent autophagic ...
Microcystin-LR is a selective inhibitor of protein phosphatase 2A (PP2A) (IC50= 0.04 nM) and will completely inhibit this enzyme without affecting PP1 when used...
Methotrexate(WR19039; CL14377) can interfere with the growth of certain cells of the body, especially cells that reproduce quickly, such as cancer cells, bone m...
an anesthetic acting on the nerve endings, with a good selectivity on sensory nerves; lowers arterial pressure; vasodilator. Tropane alkaloid , from plants of t...
Diplacine is a nicotinic cholinoreceptor antagonist at the neuromuscular junction.
Noscapine is often used as an antitussive medication.
C20-diterpenoid alkaloid , from the Ranunculaceae family,an antiarrhythmic.
Mitomycin C is a DNA crosslinking agent that inhibits DNA synthesis and induces apoptosis in a variety of cells.