|Product Name||(R)-(+)--Lipoic acid|
|Synonyms||(R)-6,8-Dithiooctanoic acid, (R)-6,8-Thioctic acid, (R)-(+)-1,2-Dithiolane-3-pentanoic acid|
|Description||Lipoic Acid, an organosulfur compound, is widely used as dietary supplements and antioxidant. It has been also found to influence the activity of nuclear factor kappa-B.|
Sodium salicylate is used in medicine as an analgesic and antipyretic.
QNZ (EVP4593) shows potent inhibitory activity toward both NF-κB activation and TNF-α production with IC50 of 11 nM and 7 nM, respectively.
CID-2858522 selectively inhibits the NF-κB pathway induced by PKC, operating downstream of PKC but upstream of IKKbeta, without inhibiting other NF-kappaB activ...
Emodin is a naturally occurring anthraquinone present in the roots and barks of numerous plants. It exerts antiproliferative effects in cancer cells that are re...
Recoflavone, also referred to DA 6034, is a synthetic flavonoid derivative known to possess anti-inflammatory activity in phase Ⅲ clinical trials for the treatm...
PNRI-299 is a selective AP-1 transcription inhibitor without affecting NF-kappaB transcription or thioredoxin.
Edasalonexent, also known as CAT-1004, is a NF-kappa B inhibitor under the development of Catabasis Pharmaceuticals and Sarepta Therapeutics. It is a Inflammati...
Adjudin, formerly called as AF-2364, an analog of lonidamine， attenuates microglia activation by suppression of the NF-κB pathway. Adjudin has potent anti-sperm...
Didox, synthetic antioxidant, is a strong inhibitor of ribonucleotide reductase (RR) that has been found to reduce the levels of oxidative injury markers in the...
Oleandrin, also known as PBI-05204, is a lipid soluble cardiac glycoside with potential antineoplastic activity. Upon administration, oleandrin specifically bin...
Harpagoside, isolated from the Harpagophytum procumbens (Devil's Claw) root or Crophularia ningpoensis Hemsl (Figwort), inhibited lipopolysaccharide-induced mRN...
Pyrrolidinedithiocarbamate ammonium is a selective NF-κB inhibitor, inducing apoptosis in rat smooth muscle cells and inhibits apoptosis in leukemia HL-60 cells...
Lipoic Acid, an organosulfur compound, is widely used as dietary supplements and antioxidant. It has been also found to influence the activity of nuclear factor...
JSH-23 is a nuclear factor-kappa B (NF-κB) nuclear translocation inhibitor. JSH-23 inhibits LPS and cytokine-induced nuclear translocation of the p65 subunit of...
Andrographolide is a labdane diterpenoid that is the main bioactive component of the medicinal plant Andrographis paniculata.
Prostratin is an activator of protein kinase C (PKC) and also an activator of nuclear factor KB (NF-KB) mediated through activation of the IKKs (IKB kinases). I...
Eupatilin, isolated from the leaves of Artemisia argyi Levl.et Vant, inhibits the signalling of MAPK, IKK, NF-κB and eotaxin-1 in bronchial epithelial cells, le...
Methysticin, the first Kava-pyrone isolated from the active constituents of rhizome extracts from Piper methysticum-a shrub indigenous to South Pacific islands,...