Mebicyphat is shown to be a non-competitive GABA antagonist. Blocks GABA gated Cl- channels, and is shown to inhibit dihydropicrotoxin
DM4 is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates.
Ca2+-Activated K+ Channel Blocker
Synthetic, nicotinic AChR. Rigid bicyclic analog of TMA and TEA.
Nitrodienamine, an inhibitor of Ca2+/Mg2+ ATPase.
Agitoxin-2 is a potent and selective blocker of the Shaker type voltage-gated Kv1.3 and Kv1.1 channels. Agitoxin-2 inhibits Kv1.3 with an IC50 value of around 2...
Okadaic acid is a marine sponge toxin which potently inhibits certain serine/threonine protein phosphatases. This cell permeable inhibitor targets the multiple ...
Duocarmycin SA is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Graveoline isolated from ethanolic extract of Ruta graveolens triggers apoptosis and autophagy in skin melanoma cells: a novel apoptosis-independent autophagic ...
Sesquiterpene lactone , from plants of the Compositae family, an antiatherosclerotic, angioprotective, hypolipidemic and anti-inflammatory.
Scyllatoxin (also leiurotoxin I) is a toxin, from the scorpion Leiurus quinquestriatus hebraeus, which blocks small-conductance Ca2+-activated K+ channels.
Kaliotoxin (1-37)NH2 is a selective voltage-dependent K+ channels blocker, a blocker of Ca2+-activated K+ channels of high conductance and some voltage-dependen...
SNX-482 has been isolated from the venom of the Spider Hysterocrates gigas (African tarantula). SNX-482 modulates the R-type current associated with the class α...
An anthelmintic: blocks the enzymatic process responsible for the absorption of glucose by parasites, causing their death. Benzimidazole derivative , synthetic.
A methyl easter of Okadaic acid. Okadaic acid is a marine sponge toxin which potently inhibits certain serine/threonine protein phosphatases.
Pinocembrin is a flavanoid with antioxidant activity found in damiana, honey, and propolis. Recent studies show that Pinocembrin maybe be a therapeutic option i...
a CNS stimulant. Alkaloid, , purified from plants of Coffea genus, Rubiaceae.
Norfluorocurarine is a peripheral vasodilator that increases blood flow to the brain (sold under the trademark Oxybral SR) .<br/>Generic drugs containing vincam...
An anticonvulsant which reduces motor activity, enhances the effects of alcohol, ether and barbiturates. Quinoline alkaloid , from plants of the Rutaceae family...