Potent antagonist for α7-containing neuronal nicotinic receptors (Ki = 1.4 nM). Interacts with α4β2 and α6β2 receptors at concentrations > 40 nM. Attenuates MET...
organophosphoric inhibitor, SA-152, on the fibrinogen-coagulating and TAME-esterase activity of bovine α-thrombin.
Taltobulin trifluoroacetate (HTI-286; SPA-110) is an analogue of Hemiasterlin; potent tubulin inhibitor; ADCs cytotoxin.
DM4 is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates.
Norfluorocurarine is a peripheral vasodilator that increases blood flow to the brain (sold under the trademark Oxybral SR) .<br/>Generic drugs containing vincam...
C19-norditerpenoid alkaloid , from plants of the Ranunculaceae family, a potent antiarrhythmic, antifibrillatory; Na+ channel blocker in cardiomyocytes.
[Tyr2]-Scyllatoxin allows labelling by iodination. 31-amino acid polypeptide with 3 disulfide bridges. , synthetic, originally from Leiurus quinquestriatus hebr...
A highly active peripheral M2-cholinoblocker alkaloid. Imperialine is extracted from Petilium eduardi and Petilium raddeanae (Liliaceae family)
Tetrahydroberberine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Tetrahydroberber...
Ansamitocin P-3, a potent anti-tumor maytansinoid found in Actinosynnema pretiosum, is a maytansine analog which displays potent cytotoxicity against the human ...
Synthetic, an inhibitor of monoamine oxydase.Enhances the toxicity of the Phenamine group and of Tryptamine.
Ryanodine High Purity
Potent inhibitor of Ca2+ release from sarcoplasmic reticulum
A methyl easter of Okadaic acid. Okadaic acid is a marine sponge toxin which potently inhibits certain serine/threonine protein phosphatases.
Bicyclic diterpenoid of the clerodane series
Synthetic, an inhibitor of high-affinity choline uptake (HAChU) in synaptosomes.
Anti-tumor effect of hernandezine and other components extracted from Thalictrum glandulosissimum.
Seco-Duocarmycin DMG is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
A potent non-competitive GABA antagonist in mammalian, molluscan and insects; convulsant;laboratory insecticide.
Ca2+-Activated K+ Channel Blocker
Melamine is a widely used, broad-spectrum benzimidazole fungicide and a metabolite of benomyl. It is also employed as a casting worm control agent in amenity tu...