1.Transfer factors of natural radionuclides and 137Cs from soil to plants used in traditional medicine in central Serbia.
Djelic G1, Krstic D2, Stajic JM1, Milenkovic B1, Topuzovic M1, Nikezic D1, Vucic D3, Zeremski T4, Stankovic M1, Kostic D1. J Environ Radioact. 2016 Apr 12;158-159:81-88. doi: 10.1016/j.jenvrad.2016.03.028. [Epub ahead of print]
Transfer factors of natural radionuclides and 137Cs from soil to plants used in traditional medicine were determined. The transfer factors (TF) were calculated as Bq kg-1 of dry plant per Bq kg-1 of dry soil. Mass activity concentrations of 226Ra, 232Th, 40K and 137Cs in soil and plant samples were measured with high purity germanium detector (HPGe). The concentrations of As, Co, Cr, Cu, Mn, Ni, Pb and Zn were determined, as well as the cation exchange capacity (CEC) and the content of exchangeable cations (Ca, Mg, K, Na). Wide ranges of values were obtained for all the metals, especially for Cr and Ni. The Absalom model was used for determination of the amount of 137Cs transferred from soil to plant based on soil characteristics such as pH, exchangeable potassium, humus and clay contents. The estimated transfer factors were in the range from 0.011 to 0.307 with an arithmetic mean of 0.071, median of 0.050, geometric mean of 0.053 and geometric standard deviation (GSD) of 2.
2.Combined Effects of High-Dose Bisphenol A and Oxidizing Agent (KBrO3) on Cellular Microenvironment, Gene Expression, and Chromatin Structure of Ku70-deficient Mouse Embryonic Fibroblasts.
Gassman NR1, Coskun E2,3, Jaruga P2, Dizdaroglu M2, Wilson SH1. Environ Health Perspect. 2016 Apr 15. [Epub ahead of print]
BACKGROUND: Exposure to bisphenol A (BPA) has been reported to alter global gene expression, induce epigenetic modifications, and interfere with complex regulatory networks of cells. In addition to these reprogramming events, we have demonstrated that BPA exposure generates reactive oxygen species and promotes cellular survival when co-exposed with the oxidizing agent potassium bromate (KBrO3).
3.Successful Treatment of Sodium Oxalate Induced Urolithiasis with HelichrysumFlowers.
Onaran M1, Orhan N2, Farahvash A1, Ekin HN2, Kocabıyık M3, Gönül İI4, Şen İ1, Aslan M5. J Ethnopharmacol. 2016 Apr 13. pii: S0378-8741(16)30194-5. doi: 10.1016/j.jep.2016.04.003. [Epub ahead of print]
ETHNOPHARMACOLOGICAL RELEVANCE: Helichrysum (Asteraceae) flowers, known as "altın otu, yayla çiçeği, kudama çiçeği", are widely used to remove kidney stones and for their diuretic properties in Turkey.
4.Efficacy and Safety of Vasopressin Receptor Antagonists for Euvolemic or Hypervolemic Hyponatremia: A Meta-Analysis.
Zhang X1, Zhao M, Du W, Zu D, Sun Y, Xiang R, Yang J. Medicine (Baltimore). 2016 Apr;95(15):e3310. doi: 10.1097/MD.0000000000003310.
Hyponatremia, defined as a nonartifactual serum sodium level <135 mmol/L, is the most common fluid and electrolyte abnormality in clinical practice. Traditional managements (fluid restriction, hypertonic saline and loop diuretics, etc.) are difficult to maintain or ineffective. Recently, vasopressin receptor antagonists (VRAs) have shown promise for the treatment of hyponatremia.We aimed to conduct a meta-analysis to evaluate the efficacy and safety of VRAs in patients with euvolemic or hypervolemic hyponatremia. We searched Pubmed, Cochrane Library, Web of Science and Springer, etc. (latest search on June 4, 2015) for English publications with randomized controlled trials. Two authors independently screened the citations and extracted data. We calculated pooled relative risk (RR), risk difference (RD), weighted mean difference (WMD) or standard mean difference (SMD), and 95% confidence intervals (CIs) by using random and fixed effect models.