Estrogenic activity; half agonist of estradiol receptors. Complex esters of phenolcarbon acids, , from plants of the Ferula genus, Umbelliferae.
A highly active peripheral M2-cholinoblocker alkaloid. Imperialine is extracted from Petilium eduardi and Petilium raddeanae (Liliaceae family)
Combretastatin A4, under the IUPAC name 2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol, inhibits tubulin polymerization (IC50= 2.2 μM). It has demons...
Lycorine is a toxic crystalline alkaloid found in various Amaryllidaceae species, such as the cultivated bush lily , surprise lilies, and daffodils. It may be h...
Quinoline Alkaloid Extracted from Haplophyllum bucharicum
β-Bungarotoxin is a form of bungarotoxin that is fairly common in Krait (Bungaros multicinctus) venoms. A pre-synaptic toxin with enzymatic activity.
Syntheticquinazolone alkaloid, inhibiting cholinesterase activity in vitro.
Complex of lanthanide element,an anticoagulant. The lanthanide element from Glutasam replaces calcium in its complex with prothrombine, thus preventing the form...
(Dap22)-ShK (ShK Dap22) peptide is a synthetic derivative of the well-known ShK toxin isolated from the venom of the Carribean sea anemone Stoichactis helianthu...
Calicheamicin is a potent DNA-binding cytotoxic antibiotic.Calicheamicin being the most notable enediyne antitumor antibiotics derived from the bacterium Microm...
An excitatory scorpion toxin. Polypeptide, of 77 amino acids cross-linked by 4 disulfide bridges. Recombinant toxin produced in<br/>Escherichia coli initialy fr...
Conantokin-G is a conopeptide that has been isolated from the venom of the cone Conus geographus. Conantokin-G selectively inhibits NR2B containing N-methyl-D-a...
22-amino acid peptide with a strongly basic character and 2 disulfide bridges, , from Apis mellifera bee venom, a blocker of voltage-sensitive K+ channels with ...
Harmine is a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds. It occurs in a number of different plants, most notably the Middl...
Scyllatoxin (also leiurotoxin I) is a toxin, from the scorpion Leiurus quinquestriatus hebraeus, which blocks small-conductance Ca2+-activated K+ channels.
Anti-inflammatory, antioxidant and free radical scavenger. Inhibits LPS-induced TNF-α, IL-6 and inducible nitric oxide production and blocks NF-κB and AP-1 acti...
Taltobulin trifluoroacetate (HTI-286; SPA-110) is an analogue of Hemiasterlin; potent tubulin inhibitor; ADCs cytotoxin.
An inhibitor of MAO.
Microcystin-RR inhibits PP1C, PP1γ, and PP2A with Ki values of 0.15, 0.24, and 0.018 nM, respectively.
Paclitaxel is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells.