PNU-159682 - CAS 202350-68-3
Not Intended for Therapeutic Use. For research use only.
Category:
ADCs
Product Name:
PNU-159682
Catalog Number:
202350-68-3
CAS Number:
202350-68-3
Description:
PNU-159682 is a major active metabolite of nemorubicin (MMDX) in human liver microsomes. PNU-159682 showed > 3,000-fold cytotoxic than its parent compound(MMDX and doxorubicin).
Molecular Weight:
627.64
Molecular Formula:
C32H37NO12
COA:
Inquire
MSDS:
Inquire
Tag:
ADCs Cytotoxin
Chemical Structure
CAS 202350-68-3 PNU-159682

Related ADCs Cytotoxin Products


CAS 23214-92-8 Doxorubicin

Doxorubicin
(CAS: 23214-92-8)

Doxorubicin(Adriamycin) is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.

CAS 33069-62-4 Paclitaxel

Paclitaxel
(CAS: 33069-62-4)

Paclitaxel is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells.

CAS 509-24-0 Songorine

Songorine
(CAS: 509-24-0)

C20-diterpenoid alkaloid from plants of the Aconitum genus, Ranunculaceae. Adrenergic and Serotonergic stimulant; CNS stimulant; antiarrhythmic.

CAS 75433-28-2 Laticauda semifasciata III

Laticauda semifasciata III
(CAS: 75433-28-2)

Polypetide, an antagonist of the nicotinic acetylcholine receptor at the neuromuscular junction with a weaker affinity to the receptor than Erabutoxins a and b.

CAS 7348-26-7 Oxylidin

Oxylidin
(CAS: 7348-26-7)

Synthetic, a weak AChR antagonist.

CAS 205304-86-5 Tubulysin A

Tubulysin A
(CAS: 205304-86-5)

Tubulysin A is a novel antibiotic, which is anti-microtubule, anti-mitotic, apoptosis inducer, anticancer, anti-angiogenic, and antiproliferative. Tubulysins sh...

CAS 107452-89-1 omega conotoxin MVIIA

omega conotoxin MVIIA
(CAS: 107452-89-1)

ω conotoxin MVIIA (omega conotoxin MVIIA) has been isolated from the venom of the cone Conus magus. Omega-conotoxins act at presynaptic membranes, they bind and...

CAS 10180-88-8 Austricine

Austricine
(CAS: 10180-88-8)

A hypolipidemic, antiatherosclerotic, anti-inflammatory agent, with angioprotective and hepatoprotective activity; antiulcerous. Sesquiterpene lactone , from pl...

3-beta-bromo-Imperialine
(CAS: 176039-27-3)

M2 muscarinic receptor antagonist; myorelaxant. Steroid alkaloid derivative of Imperialine from the plant Petilium eduardi, and P. raddeanae.

CAS 12542-36-8 Gossypol Acetic Acid

Gossypol Acetic Acid
(CAS: 12542-36-8)

an antiviral at low concentration; antiherpes, antipsoriasis and antikeratitis, male contraceptive. Polyphenol , from plants of the Gossypium genus, Malvaceae.

Maurocalcin

Synthetic, from Scorpio maurus palmatus scorpion venom. An activator of Ca2+ release channel/ryanodine receptors. 33-mer basic peptide cross-linked by three dis...

Haplophyllidine
(CAS: 18063-21-3)

Extracted from Haplophyllum perforatum plant (Rutaceae fam.). An antiarrhythmic of first class Quinoline alkaloid

CAS 93438-65-4 Conantokin-G

Conantokin-G
(CAS: 93438-65-4)

Conantokin-G is a conopeptide that has been isolated from the venom of the cone Conus geographus. Conantokin-G selectively inhibits NR2B containing N-methyl-D-a...

CAS 83-95-4 Skimmianine

Skimmianine
(CAS: 83-95-4)

A spasmolytic agent, shows pharmacol. props. similar to 2-(Methylamino)-1-phenyl-1-propanol BCJ45-G.

CAS 18172-33-3 Cyclopiazonic Acid

Cyclopiazonic Acid
(CAS: 18172-33-3)

Cyclopiazonic acid is a mycotoxin produced by molds including certain species of Penicillium and Aspergillus. Its toxicity is linked to its ability to specifica...

CAS 63968-64-9 Artemisinin

Artemisinin
(CAS: 63968-64-9)

Artemisinin is a natural product originally isolated from plants of the genus Artemisia. It effectively kills malarial parasites of the genus Plasmodium. It is ...

Brevetoxin PbTx-9

An activator of voltage-sensitive Na+ channels, a suite of cyclic polyether compounds produced naturally by a species of dinoflagellate known as Karenia brevis....

CAS 522-97-4 DL-Tetrahydroberberine

DL-Tetrahydroberberine
(CAS: 522-97-4)

Tetrahydroberberine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Tetrahydroberber...

CAS 78111-14-5 MEOA

MEOA
(CAS: 78111-14-5)

A methyl easter of Okadaic acid. Okadaic acid is a marine sponge toxin which potently inhibits certain serine/threonine protein phosphatases.

CAS 158440-71-2 Irofulven

Irofulven
(CAS: 158440-71-2)

Irofulven is a semisynthetic sesquiterpene derivative of illudin S, a natural toxin isolated from the fungus Omphalotus illudens. Irofulven alkylates DNA and pr...