Synthetic, a neuronal nicotinic AChR antagonist.
A selective inhibitor of endoplasmic reticulum Ca2+-ATPase.
A Na+ channel blocker; potent antiarrhythmic, inhibits voltage-gated Na+ channels in rat brain synaptosomes.
It was the main alkaloid found in medicinal plants Datura metel. .
A neuronal nicotinic AChR antagonist, blocking superior cervical sympathetic ganglion
Synthetic, GABAA-gated Cl- channels blocker; non-competitive GABAA antagonist.
Monomethyl Auristatin E (MMAE) is a synthetic analog of dolastatin 10 that similarly inhibits tubulin polymerization and exhibits potent cytotoxicity. It is com...
Selective blocker of the big conductance Ca2+-activated K+ channel.
Diazoline is used for symptomatic relief of allergic symptoms caused by histamine release, including nasal allergies and allergic dermatosis.
Auristatin F is a cytotoxic tubulin modifier with potent and selective antitumor activity; MMAF analog and cytotoxin in Antibody-drug conjugates.
Scyllatoxin (also leiurotoxin I) is a toxin, from the scorpion Leiurus quinquestriatus hebraeus, which blocks small-conductance Ca2+-activated K+ channels.
GABA receptor antagonist
Diazoxide is a potassium channel activator that causes local relaxation in smooth muscle by increasing membrane permeability to potassium ions. The cellular rel...
Iron carrier Synthetic
Lycoctonine is a plant alkaloid and a precursor to the ABC ring system of taxoids.
Maitansine, a cytotoxic agent, inhibits the assembly of microtubules by binding to tubulin at the rhizoxin binding site.
Dolastatin 10 is a potent antimitotic peptide from a marine animal, strongly inhibits microtubule assembly.
Mebicyphat is shown to be a non-competitive GABA antagonist. Blocks GABA gated Cl- channels, and is shown to inhibit dihydropicrotoxin
An activator of voltage-sensitive Na+ channels, a suite of cyclic polyether compounds produced naturally by a species of dinoflagellate known as Karenia brevis....
Ganglioblocker Quaternary triethylamine derivative Synthetic