|Description||PF-06380101 is a novel cytotoxic Dolastatin 10 analogue; with excellent potencies in tumor cell proliferation assays and differential ADME properties when compared to other synthetic auristatin analogues that are used in the preparation of ADCs.|
Anhydroperforine from the seeds of Haplophyllum perforatum.
Artemether is an antimalarial for the treatment of multiple drug-resistant strains of Plasmodium falciparum malaria.
Muscarinic toxin 2 (MT2) is one member of a family of small peptides of 65 amino acid residues of around 7076 daltons in molecular weight derived from the venom...
Notexin exerts both presynaptic (blocks the release of acetylcholine) and myotoxic<br/>activities
Potent inhibitor of Ca2+ release from sarcoplasmic reticulum
Alkaloid, Tetrahydroisoquinoline, Active dopamine metabolite, Cholinesterase inhibitor
anti-hypoxic; acts on the mitochondrial respiratory chain; prevents atherosclerosis; angioprotector. Sum of polymerized Proantocyanides , from the plants of Fab...
Inhibitor of Ca2+/2H+-exchange system in liver mitochondria. , synthetic.
Maitansine, a cytotoxic agent, inhibits the assembly of microtubules by binding to tubulin at the rhizoxin binding site.
DM3 is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates.
Ruthenium red is a polycationic dye that inhibits sarcoplasmic reticulum Ca2+ release, blocks Ca2+ uptake and release from mitochondria, and prevents Ca2+ relea...
10-Deacetyl-7-xylosyl paclitaxel is a Paclitaxel derivative with improved pharmacological features and higher water solubility.
Antiarrhythmic and hypotensive; ganglion blocker; exhibits weak affinity at brain α-bungarotoxin-sensitive nicotinic acetylcholine receptors.
Psoralen is a photoactive probe that has been used to investigate nucleic acid structure and function. It intercalates into DNA and, when activated by ultraviol...
Rebaudioside A is a glycoside from the stevia plant. Rebaudioside A is used as a sweetener with sweetness about 300 times that of sugar with negligible effect o...
An inhibitor of MAO.
Argiotoxin blocks the glutamate responses and sensorimotor transmission in motoneurones of isolated frog spinal cord.
Scopolamine, a nonselective muscarinic receptor antagonist, induces distinct behaviors of attenuated motility and C-like hyperactivity.
Duocarmycin B1 is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Methotrexate(WR19039; CL14377) can interfere with the growth of certain cells of the body, especially cells that reproduce quickly, such as cancer cells, bone m...