C19-norditerpenoid alkaloid , from plants of the Ranunculaceae family, a potent antiarrhythmic, antifibrillatory; Na+ channel blocker in cardiomyocytes.
Auristatin F is a cytotoxic tubulin modifier with potent and selective antitumor activity; MMAF analog and cytotoxin in Antibody-drug conjugates.
A selective blocker of the delayed rectifier K+ channel found in virtual screening
Artesunate is a derivative of the natural product artemisinin which effectively kills the malarial parasites P. falciparum and P. vivax. It also kills trematode...
Carothane complex ester , from plants of the Umbelliferae family.
Rebaudioside A is a glycoside from the stevia plant. Rebaudioside A is used as a sweetener with sweetness about 300 times that of sugar with negligible effect o...
Dihydropyridine calcium channel blocker. Antianginal; antihypertensive.
Tubulysin M is a Tubulysin D analog with potential anti-cancer properties, used as the cytotoxic component in antibody-drug conjugates.
Photosensitizing; used for determining DNA/RNA structures in cells and microorganisms. Furocoumarin , from plants of the Psoralea genus, Leguminosae.
A potent non-competitive GABA antagonist in mammalian, molluscan and insects; convulsant;laboratory insecticide.
Staurosporine is broad spectrum protein kinase inhibitor. Enzymes inhibited include protein kinase C (IC50 = 3 nM), protein kinase A (IC50 = 7 nM), p60v-src tyr...
Cyclopiazonic acid is a mycotoxin produced by molds including certain species of Penicillium and Aspergillus. Its toxicity is linked to its ability to specifica...
Cobra Venom Factor
A non-toxic, complement-activating component of cobra venom Three polypeptide chains with molecular masses of about 70, 50, and 30 kDa, the two large subunits b...
20-Hydroxyecdysone (ecdysterone or 20E) is a naturally occurring ecdysteroid hormone which controls the ecdysis (moulting) and metamorphosis of arthropods. It i...
An excitatory scorpion toxin. Polypeptide, of 77 amino acids cross-linked by 4 disulfide bridges. Recombinant toxin produced in<br/>Escherichia coli initialy fr...
An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin.
Monomethylauristatin F Hcl(MMAF Hcl) is an antitubulin agent that inhibit cell division by blocking the polymerization of tubulin; lower cytotoxic activity than...
Quinoline alkaloid , from plants of the Rutaceae family, an anticonvulsant; causes hypothermia; inhibits the reaction of orientation; prevents cardiac arrhythmi...
A scorpion alpha-insect toxin, which prolongs the evoked action potential by an inhibition of sodium current inactivation in insects and mammals.
Okadaic acid is a marine sponge toxin which potently inhibits certain serine/threonine protein phosphatases. This cell permeable inhibitor targets the multiple ...