Used as an antihypertensive and antianginal. A dihydorpyridine calcium channel blocker.
Saxitoxin (STX) is a potent neurotoxin and the best-known paralytic shellfish toxin (PST). Ingestion of saxitoxin, usually by consumption of shellfish contamina...
GABA receptor antagonist
Potent blocker of voltage-sensitive K+ channels (IC50 values are 0.1, 1.1 and 25 nM for KV1.3, KV1.1 and KV1.2 channels) respectively). Also inhibits Ca2+-activ...
A muscarinic receptors antagonist.
An antagonist of the nicotinic acetylcholine receptor at the neuromuscular junction. Erabutoxin B from Laticauda semifasciata (Sea Snake)
A scorpion alpha-insect toxin, which prolongs the evoked action potential by an inhibition of sodium current inactivation in insects and mammals.
Non-selective K+ channel blocker.
An ATPase inhibitor.
Combretastatin A4, under the IUPAC name 2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol, inhibits tubulin polymerization (IC50= 2.2 μM). It has demons...
Bicyclic diterpenoid of the clerodane series
Estrogenic activity; half agonist of estradiol receptors. Complex esters of phenolcarbon acids, , from plants of the Ferula genus, Umbelliferae.
DM3 is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates.
Tubulysin B is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
an antagonist of the nicotinic acetylcholine receptor at the neuromuscular junction. Erabutoxin B from Laticauda semifasciata (Sea Snake)
Methotrexate(WR19039; CL14377) can interfere with the growth of certain cells of the body, especially cells that reproduce quickly, such as cancer cells, bone m...
Nitrodienamine, an inhibitor of Ca2+/Mg2+ ATPase.
A microtubule-disrupting agent.
Carothane complex ester , from plants of the Umbelliferae family.
An inhibitor of serine proteinases of broad spectrum.