Nitroxinil - CAS 1689-89-0

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Category
APIs for Veterinary
Product Name
Nitroxinil
Catalog Number
1689-89-0
Synonyms
NITROXINIL; NITROXYNIL; 4-hydroxy-3-iodo-5-nitro-benzonitril; dovenix; 4-CYANO-2-IODO-6-NITROPHENOL; 4-HYDROXY-3-IODO-5-NITROBENZONITRILE; NITROXINYL; Benzonitrile, 4-hydroxy-3-iodo-5-nitro-
CAS Number
1689-89-0
Molecular Weight
290.01
Molecular Formula
C7H3IN2O3
COA
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MSDS
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Structure
CAS 1689-89-0 Nitroxinil
Specification
Purity
98%
Density
2.24 g/cm3
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Reference Reading
1. Efficacy of an experimental fasciolicide against immature and mature Fasciola hepatica in artificially infected calves
Y. Vera Montenegro, F. Ibarra Velarde, E. Liebano Hernandez, H. Quiroz Romero. Parasitol Res (2004) 92: 211–214
More recently, Ibarra et al. (2001) have observed that TCB showed lower fasciolicide activity (71.7%) against immature stages of F. hepatica when tested at recommended doses in cattle naturally infected with the trematode. In our study, compound alpha showed higher activity against flukes aged 4 and 6 weeks. In another study Vera et al. (2003) determined the per- centage of fluke egg reduction in naturally infected cattle, obtaining a 97% efficacy at the dose rate of 12 mg/kg by mouth. It is also important to note that compound alpha overcomes the problem of lack of activity shown against immature stages by older fasciolicides such as meniclofolan, nitroxinil, rafoxanide, albendazole, closantel and clorsulon, among others (Cordero del Campillo and Rojo Vazquez 1999).
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