Ionotropic GABAA receptors are ligand-gated ion channels that facilitate the passing of chloride ions across the cell membrane and promote an inhibitory influen...
Ryanodine High Purity
Potent inhibitor of Ca2+ release from sarcoplasmic reticulum
Saxitoxin (STX) is a potent neurotoxin and the best-known paralytic shellfish toxin (PST). Ingestion of saxitoxin, usually by consumption of shellfish contamina...
Potent ganglioblocker, a neuronal nicotinic AChR antagonist. .
Quinoline Alkaloid Extracted from Haplophyllum bucharicum
Alkaloid from reticuline and is a precursor of berberine.It has also been found to be a GABAA receptor agonist.
Psoralen is a photoactive probe that has been used to investigate nucleic acid structure and function. It intercalates into DNA and, when activated by ultraviol...
Napelline is a diterpenoid alkaloid from plants of the Aconitum,genus, a potent antiarrhythmic with weak hypotensive and N-cholinoblocking effects.
Synthetic organophosphorous compound, a non-competitive GABA antagonist; potent convulsant: causes epileptoform seizures.
Auristatin E is a synthetic analog of dolastatin 10. Auristatin E is a highly potent antimitotic agent.Auristatin E inhibits tubulin polymerization. Auristatin ...
Amiloride HCl is a relatively selective inhibitor of the epithelial sodium channel, used in the management of hypertension and congestive heart failure.
Laticauda semifasciata III
Polypetide, an antagonist of the nicotinic acetylcholine receptor at the neuromuscular junction with a weaker affinity to the receptor than Erabutoxins a and b.
Askendoside D presents a high selectivity for the cardiac Na+/K+-ATPase, with practically no activity on brain or kidney Na+/K+-ATPases, as compared with other ...
A highly active peripheral M2-cholinoblocker alkaloid. Imperialine is extracted from Petilium eduardi and Petilium raddeanae (Liliaceae family)
Daunorubicin(RP13057) inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0.02 μM.
Potent, cell-permeable, IP3-independent intracellular calcium releaser. Blocks the transient increase in intracellular Ca2+ induced by angiostatin and endostati...
Synthetic, nicotinic AChR. Rigid bicyclic analog of TMA and TEA.
Ducamycin Analog is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Inhibitor of Ca2+/2H+-exchange system in liver mitochondria. , synthetic.
Quinoline alkaloid , from plants of the Rutaceae family, an anticonvulsant; causes hypothermia; inhibits the reaction of orientation; prevents cardiac arrhythmi...