Nicergoline - CAS 27848-84-6

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Category
APIs
Product Name
Nicergoline
Catalog Number
27848-84-6
Synonyms
[(6aR,9R,10aS)-10a-methoxy-4,7-dimethyl-6a,8,9,10-tetrahydro-6H-indolo[4,3-fg]quinoline-9-yl]methyl 5-bromopyridine-3-carboxylate Aventis Brand of Nicergoline betapharm Brand of Nicergoline Circo Maren Circo-Maren ct Arzneimittel Brand of Nicergoline ct-A
CAS Number
27848-84-6
Description
Nicergoline, an ergot derivative, inhibits the postsynaptic α1-adrenoceptors on vascular smooth muscle leading to inhibition of the vasoconstrictor effect of catecholamines. Nicergoline can be used to treat age-dependent cognitive impairment incluing Alzh
Molecular Weight
484.39
Molecular Formula
C24H26BrN3O3
Quality Standard
EP
COA
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MSDS
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Canonical SMILES
CN1CC(CC2(C1CC3=CN(C4=CC=CC2=C34)C)OC)COC(=O)C5=CC(=CN=C5)Br
InChI
1S/C24H26BrN3O3/c1-27-13-17-8-21-24(30-3,19-5-4-6-20(27)22(17)19)9-15(12-28(21)2)14-31-23(29)16-7-18(25)11-26-10-16/h4-7,10-11,13,15,21H,8-9,12,14H2,1-3H3/t15-,21-,24+/m1/s1
InChIKey
YSEXMKHXIOCEJA-FVFQAYNVSA-N
Targets
Adrenergic Receptor
Structure
CAS 27848-84-6 Nicergoline
Specification
Purity
98%
Boiling Point
594.4±50.0 °C | Condition: Press: 760 Torr
Melting Point
136-138 °C
Density
1.47±0.1 g/cm3
Appearance
White Solid
Storage
Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -21℃ for long term (months to years).
Solubility
Soluble to 100 mM in DMSO
Shelf Life
2 years
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