An activator of voltage-sensitive Na+ channels, a suite of cyclic polyether compounds produced naturally by a species of dinoflagellate known as Karenia brevis....
Diacetylkorseveriline is an antiarrhythmic (classes i and iv), belonging to a novel structural class. effective against arrhythmia caused by aconitine,CaCl2, el...
Diterpenoid alkaloids from the roots of Delphinium scabriflorum.
Synthetic, a selective irreversible inhibitor of carboxylesterases
Potent ganglioblocker, a neuronal nicotinic AChR antagonist. .
A methyl easter of Okadaic acid. Okadaic acid is a marine sponge toxin which potently inhibits certain serine/threonine protein phosphatases.
Sesquiterpene lactone , from plants of the Compositae family, an antiatherosclerotic, angioprotective, hypolipidemic and anti-inflammatory.
A microtubule-disrupting agent.
C19-norditerpenoid alkaloid , from plants of the Ranunculaceae family, a potent antiarrhythmic, antifibrillatory; Na+ channel blocker in cardiomyocytes.
Imperialine is an isosteroidal alkaloid from Fritillaria thunbergii, a short-acting selective M2 muscarinic receptor antagonist.
Anti-tumor effect of hernandezine and other components extracted from Thalictrum glandulosissimum.
Triptolide is a diterpene triepoxide, immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii.
A highly active peripheral M2-cholinoblocker alkaloid. Imperialine is extracted from Petilium eduardi and Petilium raddeanae (Liliaceae family)
Conantokin-G is a conopeptide that has been isolated from the venom of the cone Conus geographus. Conantokin-G selectively inhibits NR2B containing N-methyl-D-a...
Synthetic, an inhibitor of high-affinity choline uptake (HAChU) in synaptosomes.
Sanguinarine is a toxic quaternary ammonium salt from the group of benzophenanthridine alkaloids. It is extracted from some plants, including bloodroot (Sanguin...
Synthetic, an inhibitor of monoamine oxydase.
A natural compound extracted from Phellodendron chinense, exhibits a near planar framework
Mesaconitine has antinociceptive activity through cyclic AMP and stimulation of the central β-adrenergic system.
Seco-Duocarmycin SA is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.