|Description||Microcystin-RR inhibits PP1C, PP1γ, and PP2A with Ki values of 0.15, 0.24, and 0.018 nM, respectively.|
Bicyclic analog of Ach, a weak muscarinic AChR agonist.
Agitoxin-2 is a potent and selective blocker of the Shaker type voltage-gated Kv1.3 and Kv1.1 channels. Agitoxin-2 inhibits Kv1.3 with an IC50 value of around 2...
Nitrodienamine, an inhibitor of Ca2+/Mg2+ ATPase.
Seco-Duocarmycin GA is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
a CNS stimulant. Alkaloid, , purified from plants of Coffea genus, Rubiaceae.
Gramine is a naturally occurring indole alkaloid present in several plant species. Gramine may play a defensive role in these plants, since it is toxic to many ...
Trichodesmine is a pyrrolizidine alkaloid that has neurotoxic effects and is naturally found in Crotolaria argyptiaca, a shrub plant that is native to the south...
The lanthanide element from Glutaned replaces calcium in its complex with prothrombine,<br/>thus preventing the formation of thrombine and interrupting the bloo...
An anticonvulsant which reduces motor activity, enhances the effects of alcohol, ether and barbiturates. Quinoline alkaloid , from plants of the Rutaceae family...
a nicotinic cholinoreceptor antagonist at the neuromuscular junction; curare-like ganglioblocker. Bis-quaternary quinuclidine derivative, , synthetic.
Argiotoxin blocks the glutamate responses and sensorimotor transmission in motoneurones of isolated frog spinal cord.
Turkesterone is a phytoecdysteroid possessing an 11alpha-hydroxyl group, also is an analogue of the insect steroid hormone 20-hydroxyecdysone.
Kaliotoxin (1-37)NH2 is a selective voltage-dependent K+ channels blocker, a blocker of Ca2+-activated K+ channels of high conductance and some voltage-dependen...
Ruthenium red is a polycationic dye that inhibits sarcoplasmic reticulum Ca2+ release, blocks Ca2+ uptake and release from mitochondria, and prevents Ca2+ relea...
Scyllatoxin (Leiurotoxin-1) is a neurotoxin that was originally isolated from Leiurus quinquestriatus hebraeus. Scyllatoxin binds and blocks SK channels (small ...
Seco-Duocarmycin DMG is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Quinoline alkaloid , from plants of the Rutaceae family, an anticonvulsant; causes hypothermia; inhibits the reaction of orientation; prevents cardiac arrhythmi...
Delsoline is a hypotensive alkaloid isolated from Aconitum.
SNX-482 has been isolated from the venom of the Spider Hysterocrates gigas (African tarantula). SNX-482 modulates the R-type current associated with the class α...