|Description||Methotrexate(WR19039; CL14377) can interfere with the growth of certain cells of the body, especially cells that reproduce quickly, such as cancer cells, bone marrow cells, and skin cells.|
Synthetic, a neuronal nicotinic AChR antagonist.
Diterpenoid , from plants of the Stevia genus, Compositae. Sweetener; reported as possessing anti-hypertensive effects upon hypertensive rats.
omega conotoxin MVIIA
ω conotoxin MVIIA (omega conotoxin MVIIA) has been isolated from the venom of the cone Conus magus. Omega-conotoxins act at presynaptic membranes, they bind and...
Potent ganglioblocker, a neuronal nicotinic AChR antagonist. .
A cardioselective M2-cholinoblocking compound semi-synthetic derivative of Imperialine alkaloid Derived from base alkaloid Imperialine, isolated from the plant ...
Synthetic, nicotinic AChR. Rigid bicyclic analog of TMA and TEA.
DM4 is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates.
Diamine oxidase activator. Na+ channels blocker.
Synthetic, a potent inhibitor of high-affinity choline uptake (HAChU) in synaptosomes.
Askendoside D presents a high selectivity for the cardiac Na+/K+-ATPase, with practically no activity on brain or kidney Na+/K+-ATPases, as compared with other ...
α-Dendrotoxin inhibits 4-AP sensitive, inactivating voltage-gated<br/>K+ channels (KV1.1, KV1.2 and KV1.6).
Amaryllidaceae alkaloid from plants of the Amaryllidaceae family. A hypotensive, sedative. Amaryllidaceae alkaloid , from plants of the Amaryllidaceae family.
A Norditerpenoid alkaloid. Nicotinic receptor antagonist at the neuromuscular junction and vegetative ganglia; hypotensive. Diterpene alkaloid , from plants of ...
Combretastatin A4, under the IUPAC name 2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol, inhibits tubulin polymerization (IC50= 2.2 μM). It has demons...
α-Cobratoxin is a substance of the venom of certain Naja cobras. It is a nicotinic acetylcholine receptor (nAChR) antagonist which causes paralysis by preventin...
Topotecan has been used as a positive control for the identification and analysis of HIF-1α and VEGF inhibitors in human glioma cells under hypoxic conditions. ...
It was the main alkaloid found in medicinal plants Datura metel. .
ω-conotoxin MVIIC (omega conotoxin MVIIC) is a conotoxin that has been isolated from the venom of the cone Conus magus. ω-conotoxin MVIIC is a blocker of P/Q an...
Aporphine alkaloid , from plants of the Papaveraceae family, a CNS stimulant which enhances the analeptic effects of caffeine and strychnine.
Quinoline alkaloid , from plants of the Rutaceae family, an anticonvulsant; causes hypothermia; inhibits the reaction of orientation; prevents cardiac arrhythmi...