|Description||A methyl easter of Okadaic acid. Okadaic acid is a marine sponge toxin which potently inhibits certain serine/threonine protein phosphatases.|
Trichodesmine is a pyrrolizidine alkaloid that has neurotoxic effects and is naturally found in Crotolaria argyptiaca, a shrub plant that is native to the south...
Deltaline has a lycoctonine carbon-atom skeleton with four six-membered rings and three five-membered rings among; three of the six-membered rings adopt chair c...
A Norditerpenoid alkaloid. Nicotinic receptor antagonist at the neuromuscular junction and vegetative ganglia; hypotensive. Diterpene alkaloid , from plants of ...
TTX is a potent marine-derived neurotoxin that reversibly inhibits the inward sodium current through voltage-activated sodium (NaV) channels, blocking nerve and...
An anesthetic acting on the nerve endings, with a good selectivity on sensory nerves; lowers arterial pressure; vasodilator. Tropane alkaloid , from plants of t...
Seco-Duocarmycin DME is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Irofulven is a semisynthetic sesquiterpene derivative of illudin S, a natural toxin isolated from the fungus Omphalotus illudens. Irofulven alkylates DNA and pr...
Duocarmycin B1 is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Monomethyl Auristatin E (MMAE) is a synthetic analog of dolastatin 10 that similarly inhibits tubulin polymerization and exhibits potent cytotoxicity. It is com...
Doxorubicin (Adriamycin) is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.
A spasmolytic agent, shows pharmacol. props. similar to 2-(Methylamino)-1-phenyl-1-propanol BCJ45-G.
DM4 is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates.
Synthetic, nicotinic AChR. Rigid bicyclic analog of TMA and TEA.
Margatoxin (MgTx) is a component of the venom of Scorpio Centruroides margaritatus. Margatoxin preferentially inhibits voltage-dependent potassium channels Kv1....
Agitoxin-2 is a potent and selective blocker of the Shaker type voltage-gated Kv1.3 and Kv1.1 channels. Agitoxin-2 inhibits Kv1.3 with an IC50 value of around 2...
Anticoagulant: irreversible inhibits serine proteinase a-thrombine. Fluorocontaining phosphonate, synthetised.
C20-diterpenoid alkaloid , from the Ranunculaceae family,an antiarrhythmic.
A neuronal nicotinic AChR antagonist, blocking superior cervical sympathetic ganglion
Potent, reversible acetylcholinesterase inhibitor